Generation and validation of a novel multitarget small molecule in glioblastoma

Abstract The development of multitarget small molecules (MSMs) has emerged as a powerful strategy for the treatment of multifactorial diseases such as cancer. Glioblastoma is the most prevalent and malignant primary brain tumor in adults, which is characterized by poor prognosis and a high heterogen...

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Main Authors: Aizpea Artetxe-Zurutuza, Nerea Iturrioz-Rodriguez, Joseba Elizazu, Mireia Toledano-Pinedo, Alicia Porro-Pérez, Irati De Goñi, Alejandro Elua-Pinin, Linda Schäker-Hübner, Mikel Azkargorta, Felix Elortza, Isabel Iriepa, Francisco Lòpez-Muñoz, Veronica Moncho-Amor, Finn K. Hansen, Nicolás Sampron, Jose Luis Marco-Contelles, Ander Matheu
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07569-1
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