Leucine‐Rich Repeat Containing 15 Promotes the Inflammatory Response in Rheumatoid Arthritis by Regulating NF‐κB Pathway

Leucine‐Rich Repeat Containing 15 Promotes the Inflammatory Response in Rheumatoid Arthritis by Regulating NF‐κB Pathway

ABSTRACT Purpose To explore the influence and molecular mechanism of leucine‐rich repeat containing 15 (LRRC15) in rheumatoid arthritis (RA) model induced by collagen‐induced arthritis (CIA) in rats and interleukin‐1 beta (IL‐1β) treated fibroblast‐like synoviocytes (FLSs). Methods LRRC15 expression...

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Bibliographic Details
Main Authors: Miaomiao Xin, Guangtao Xia, Xin Guan, Guangmin Xi, Min Fu
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Immunity, Inflammation and Disease
Subjects:
fibroblast‐like synoviocytes
inflammatory response
Lrrc15
NF‐κB pathway
rheumatoid arthritis
Online Access:https://doi.org/10.1002/iid3.70220
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