Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent

This review provides a comprehensive exploration of the Psychotria species, a genus of plants known for their medicinal properties and traditional uses. The focus is on the species’ ethnomedicinal applications, their potential as an antidiabetic agent, the pharmacologically active antidiabetic comp...

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Main Authors: Sharifah Nurul Akilah Syed Mohamad, Alfi Khatib, Siti Zaiton Mat Soád, Qamar Uddin Ahmed, Zalikha Ibrahim
Format: Article
Language:English
Published: IIUM Press, International Islamic University Malaysia 2025-01-01
Series:Journal of Pharmacy
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Online Access:https://journals.iium.edu.my/ktn/index.php/jp/article/view/341
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author Sharifah Nurul Akilah Syed Mohamad
Alfi Khatib
Siti Zaiton Mat Soád
Qamar Uddin Ahmed
Zalikha Ibrahim
author_facet Sharifah Nurul Akilah Syed Mohamad
Alfi Khatib
Siti Zaiton Mat Soád
Qamar Uddin Ahmed
Zalikha Ibrahim
author_sort Sharifah Nurul Akilah Syed Mohamad
collection DOAJ
description This review provides a comprehensive exploration of the Psychotria species, a genus of plants known for their medicinal properties and traditional uses. The focus is on the species’ ethnomedicinal applications, their potential as an antidiabetic agent, the pharmacologically active antidiabetic compounds possessed, and their toxicological profiles. The escalating global prevalence of diabetes underscores the need for alternative therapeutic agents. The Psychotria species, with their antidiabetic properties, present a promising area of research. The traditional medicinal uses of the Psychotria species across various cultures are examined, providing valuable insights for the development of novel treatments. This review delves into the mechanisms through which these species exert their antidiabetic effects especially Psychotria malayana. The review discusses the pharmacologically active compounds unique to these species, which are of considerable interest for drug development in diabetes treatment. A summary of these studies and their implications is presented. Finally, the review addresses the toxicological studies on the Psychotria species, assessing their safety as therapeutic agents.
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institution Kabale University
issn 2773-5664
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publisher IIUM Press, International Islamic University Malaysia
record_format Article
series Journal of Pharmacy
spelling doaj-art-5bec50e547c2455f8298785519c162cd2025-01-31T01:08:56ZengIIUM Press, International Islamic University MalaysiaJournal of Pharmacy2773-56642025-01-015110.31436/jop.v5i1.341Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent Sharifah Nurul Akilah Syed Mohamad0Alfi Khatib1Siti Zaiton Mat Soád2Qamar Uddin Ahmed3Zalikha Ibrahim4Pharmacognosy Research Group, Kulliyyah of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang, Malaysia.Pharmacognosy Research Group, Kulliyyah of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang, Malaysia.Pharmacognosy Research Group, Kulliyyah of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang, Malaysia.Pharmacognosy Research Group, Kulliyyah of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang, Malaysia.Pharmacognosy Research Group, Kulliyyah of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang, Malaysia. This review provides a comprehensive exploration of the Psychotria species, a genus of plants known for their medicinal properties and traditional uses. The focus is on the species’ ethnomedicinal applications, their potential as an antidiabetic agent, the pharmacologically active antidiabetic compounds possessed, and their toxicological profiles. The escalating global prevalence of diabetes underscores the need for alternative therapeutic agents. The Psychotria species, with their antidiabetic properties, present a promising area of research. The traditional medicinal uses of the Psychotria species across various cultures are examined, providing valuable insights for the development of novel treatments. This review delves into the mechanisms through which these species exert their antidiabetic effects especially Psychotria malayana. The review discusses the pharmacologically active compounds unique to these species, which are of considerable interest for drug development in diabetes treatment. A summary of these studies and their implications is presented. Finally, the review addresses the toxicological studies on the Psychotria species, assessing their safety as therapeutic agents. https://journals.iium.edu.my/ktn/index.php/jp/article/view/341Psychotriaantidiabeticethnomedicinalphytochemistrytoxicity
spellingShingle Sharifah Nurul Akilah Syed Mohamad
Alfi Khatib
Siti Zaiton Mat Soád
Qamar Uddin Ahmed
Zalikha Ibrahim
Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent
Journal of Pharmacy
Psychotria
antidiabetic
ethnomedicinal
phytochemistry
toxicity
title Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent
title_full Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent
title_fullStr Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent
title_full_unstemmed Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent
title_short Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent
title_sort ethnopharmacology of psychotria potential use of p malayana jack leaves as antidiabetic agent
topic Psychotria
antidiabetic
ethnomedicinal
phytochemistry
toxicity
url https://journals.iium.edu.my/ktn/index.php/jp/article/view/341
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