DEVISING AN EXAMINATION SCHEME OF HEARING IN CHILDREN RECEIVED CHEMOTHERAPY WITH PLATINUM

Over the past few decades significant advances in the treatment of children with oncological diseases have been obtained. In this regard an issue of the life quality of patients after treatment, the problem of diagnosis and therapy of long-term complications of chemotherapy is particularly actual. P...

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Main Authors: G.S Tufatulin, Yu.S. Garbaruk
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2011-12-01
Series:Педиатрическая фармакология
Online Access:https://www.pedpharma.ru/jour/article/view/1306
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author G.S Tufatulin
Yu.S. Garbaruk
author_facet G.S Tufatulin
Yu.S. Garbaruk
author_sort G.S Tufatulin
collection DOAJ
description Over the past few decades significant advances in the treatment of children with oncological diseases have been obtained. In this regard an issue of the life quality of patients after treatment, the problem of diagnosis and therapy of long-term complications of chemotherapy is particularly actual. Purpose of the work — to develop the audiologic examination scheme of children treated with platinum drugs (carboplatin, cysplatin). We examined 46 children aged from 3 months to 18 years. As an audiological methods we used different classes of otoacoustic emissions, tympanometry, tonal threshold audiometry. In 15,2% of children with normal hearing thresholds at speech frequencies we revealed a high frequency hearing loss, and in 8,7% — a sensoneural hearing loss and in 6,5% — conductive hearing loss. During the dynamic examination the progressed deafness took place in 7 (12) children. On the base of the obtained results we determined the most optimal scheme of audiologic examination. Key words: ototoxicity, platinum drugs, otoacoustic emission hearing screening. (Pediatric pharmacology. — 2011; 8 (6): 88–92).
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series Педиатрическая фармакология
spelling doaj-art-5bebfbf09fa4409f80486b41ff9b53c52025-08-20T03:59:21ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892011-12-018688921301DEVISING AN EXAMINATION SCHEME OF HEARING IN CHILDREN RECEIVED CHEMOTHERAPY WITH PLATINUMG.S Tufatulin0Yu.S. Garbaruk1St. Petersburg State Pediatric Medical Academy of Russian Health Care DepartmentSt. Petersburg State Pediatric Medical Academy of Russian Health Care DepartmentOver the past few decades significant advances in the treatment of children with oncological diseases have been obtained. In this regard an issue of the life quality of patients after treatment, the problem of diagnosis and therapy of long-term complications of chemotherapy is particularly actual. Purpose of the work — to develop the audiologic examination scheme of children treated with platinum drugs (carboplatin, cysplatin). We examined 46 children aged from 3 months to 18 years. As an audiological methods we used different classes of otoacoustic emissions, tympanometry, tonal threshold audiometry. In 15,2% of children with normal hearing thresholds at speech frequencies we revealed a high frequency hearing loss, and in 8,7% — a sensoneural hearing loss and in 6,5% — conductive hearing loss. During the dynamic examination the progressed deafness took place in 7 (12) children. On the base of the obtained results we determined the most optimal scheme of audiologic examination. Key words: ototoxicity, platinum drugs, otoacoustic emission hearing screening. (Pediatric pharmacology. — 2011; 8 (6): 88–92).https://www.pedpharma.ru/jour/article/view/1306
spellingShingle G.S Tufatulin
Yu.S. Garbaruk
DEVISING AN EXAMINATION SCHEME OF HEARING IN CHILDREN RECEIVED CHEMOTHERAPY WITH PLATINUM
Педиатрическая фармакология
title DEVISING AN EXAMINATION SCHEME OF HEARING IN CHILDREN RECEIVED CHEMOTHERAPY WITH PLATINUM
title_full DEVISING AN EXAMINATION SCHEME OF HEARING IN CHILDREN RECEIVED CHEMOTHERAPY WITH PLATINUM
title_fullStr DEVISING AN EXAMINATION SCHEME OF HEARING IN CHILDREN RECEIVED CHEMOTHERAPY WITH PLATINUM
title_full_unstemmed DEVISING AN EXAMINATION SCHEME OF HEARING IN CHILDREN RECEIVED CHEMOTHERAPY WITH PLATINUM
title_short DEVISING AN EXAMINATION SCHEME OF HEARING IN CHILDREN RECEIVED CHEMOTHERAPY WITH PLATINUM
title_sort devising an examination scheme of hearing in children received chemotherapy with platinum
url https://www.pedpharma.ru/jour/article/view/1306
work_keys_str_mv AT gstufatulin devisinganexaminationschemeofhearinginchildrenreceivedchemotherapywithplatinum
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