Genomic Profiling by Array Comparative Genomic Hybridization Reveals Novel DNA Copy Number Changes in Breast Phyllodes Tumours

Breast phyllodes tumour (PT) is a rare fibroepithelial tumour. The genetic alterations contributing to its tumorigenesis are largely unknown. To identify genomic regions involved in pathogenesis and progression of PTs we obtained genome-wide copy number profiles by array comparative genomic hybridiz...

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Main Authors: Arno Kuijper, Antoine M. Snijders, Els M. J. J. Berns, Vibeke Kuenen-Boumeester, Elsken van der Wall, Donna G. Albertson, Paul J. van Diest
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2009-0457
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author Arno Kuijper
Antoine M. Snijders
Els M. J. J. Berns
Vibeke Kuenen-Boumeester
Elsken van der Wall
Donna G. Albertson
Paul J. van Diest
author_facet Arno Kuijper
Antoine M. Snijders
Els M. J. J. Berns
Vibeke Kuenen-Boumeester
Elsken van der Wall
Donna G. Albertson
Paul J. van Diest
author_sort Arno Kuijper
collection DOAJ
description Breast phyllodes tumour (PT) is a rare fibroepithelial tumour. The genetic alterations contributing to its tumorigenesis are largely unknown. To identify genomic regions involved in pathogenesis and progression of PTs we obtained genome-wide copy number profiles by array comparative genomic hybridization (CGH).
format Article
id doaj-art-5be97f3f3404424da4c7768023bdbc7d
institution Kabale University
issn 1570-5870
1875-8606
language English
publishDate 2009-01-01
publisher Wiley
record_format Article
series Cellular Oncology
spelling doaj-art-5be97f3f3404424da4c7768023bdbc7d2025-08-20T03:34:48ZengWileyCellular Oncology1570-58701875-86062009-01-01311313910.3233/CLO-2009-0457Genomic Profiling by Array Comparative Genomic Hybridization Reveals Novel DNA Copy Number Changes in Breast Phyllodes TumoursArno Kuijper0Antoine M. Snijders1Els M. J. J. Berns2Vibeke Kuenen-Boumeester3Elsken van der Wall4Donna G. Albertson5Paul J. van Diest6Department of Pathology, University Medical Centre Utrecht, Utrecht, The NetherlandsCancer Research Institute, University of California San Francisco, San Francisco, CA, USADepartment of Medical Oncology, Erasmus MC, Rotterdam, The NetherlandsDepartment of Pathology, Erasmus MC, Rotterdam, The NetherlandsDivision of Internal Medicine and Dermatology, University Medical Centre Utrecht, Utrecht, The NetherlandsCancer Research Institute, University of California San Francisco, San Francisco, CA, USADepartment of Pathology, University Medical Centre Utrecht, Utrecht, The NetherlandsBreast phyllodes tumour (PT) is a rare fibroepithelial tumour. The genetic alterations contributing to its tumorigenesis are largely unknown. To identify genomic regions involved in pathogenesis and progression of PTs we obtained genome-wide copy number profiles by array comparative genomic hybridization (CGH).http://dx.doi.org/10.3233/CLO-2009-0457
spellingShingle Arno Kuijper
Antoine M. Snijders
Els M. J. J. Berns
Vibeke Kuenen-Boumeester
Elsken van der Wall
Donna G. Albertson
Paul J. van Diest
Genomic Profiling by Array Comparative Genomic Hybridization Reveals Novel DNA Copy Number Changes in Breast Phyllodes Tumours
Cellular Oncology
title Genomic Profiling by Array Comparative Genomic Hybridization Reveals Novel DNA Copy Number Changes in Breast Phyllodes Tumours
title_full Genomic Profiling by Array Comparative Genomic Hybridization Reveals Novel DNA Copy Number Changes in Breast Phyllodes Tumours
title_fullStr Genomic Profiling by Array Comparative Genomic Hybridization Reveals Novel DNA Copy Number Changes in Breast Phyllodes Tumours
title_full_unstemmed Genomic Profiling by Array Comparative Genomic Hybridization Reveals Novel DNA Copy Number Changes in Breast Phyllodes Tumours
title_short Genomic Profiling by Array Comparative Genomic Hybridization Reveals Novel DNA Copy Number Changes in Breast Phyllodes Tumours
title_sort genomic profiling by array comparative genomic hybridization reveals novel dna copy number changes in breast phyllodes tumours
url http://dx.doi.org/10.3233/CLO-2009-0457
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