Genomic Profiling by Array Comparative Genomic Hybridization Reveals Novel DNA Copy Number Changes in Breast Phyllodes Tumours

Breast phyllodes tumour (PT) is a rare fibroepithelial tumour. The genetic alterations contributing to its tumorigenesis are largely unknown. To identify genomic regions involved in pathogenesis and progression of PTs we obtained genome-wide copy number profiles by array comparative genomic hybridiz...

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Bibliographic Details
Main Authors: Arno Kuijper, Antoine M. Snijders, Els M. J. J. Berns, Vibeke Kuenen-Boumeester, Elsken van der Wall, Donna G. Albertson, Paul J. van Diest
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2009-0457
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Summary:Breast phyllodes tumour (PT) is a rare fibroepithelial tumour. The genetic alterations contributing to its tumorigenesis are largely unknown. To identify genomic regions involved in pathogenesis and progression of PTs we obtained genome-wide copy number profiles by array comparative genomic hybridization (CGH).
ISSN:1570-5870
1875-8606