Assessing the Burden of Neglected Tropical Diseases in Low-Income Communities: Challenges and Solutions

Neglected tropical diseases (NTDs) represent a group of chronic and debilitating infections that affect more than one billion people, predominantly in low-income communities with limited health infrastructure. This paper analyzes the factors that perpetuate the burden of NTDs, highlighting how poor...

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Main Authors: Francesco Branda, Abdisalam Yusuf Ali, Giancarlo Ceccarelli, Mattia Albanese, Erica Binetti, Marta Giovanetti, Massimo Ciccozzi, Fabio Scarpa
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Viruses
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Online Access:https://www.mdpi.com/1999-4915/17/1/29
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author Francesco Branda
Abdisalam Yusuf Ali
Giancarlo Ceccarelli
Mattia Albanese
Erica Binetti
Marta Giovanetti
Massimo Ciccozzi
Fabio Scarpa
author_facet Francesco Branda
Abdisalam Yusuf Ali
Giancarlo Ceccarelli
Mattia Albanese
Erica Binetti
Marta Giovanetti
Massimo Ciccozzi
Fabio Scarpa
author_sort Francesco Branda
collection DOAJ
description Neglected tropical diseases (NTDs) represent a group of chronic and debilitating infections that affect more than one billion people, predominantly in low-income communities with limited health infrastructure. This paper analyzes the factors that perpetuate the burden of NTDs, highlighting how poor health infrastructure, unfavorable socioeconomic conditions and lack of therapeutic resources exacerbate their impact. The effectiveness of current interventions, such as mass drug administration (MDA) programs and improved sanitation, in reducing disease prevalence is examined. In addition, the role of climate change, which alters transmission dynamics and expands affected territories, is discussed as an emerging challenge. The analysis suggests that integrated, multisectoral approaches, including health education and infrastructure interventions, are essential to breaking the cycle of poverty and disease. Although international programs have marked significant progress, achieving elimination targets by 2030 requires sustained commitment, innovation, and increased research capacity in endemic countries.
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series Viruses
spelling doaj-art-5be60dfdac4c4ac38691367a8b8f6c422025-01-24T13:52:18ZengMDPI AGViruses1999-49152024-12-011712910.3390/v17010029Assessing the Burden of Neglected Tropical Diseases in Low-Income Communities: Challenges and SolutionsFrancesco Branda0Abdisalam Yusuf Ali1Giancarlo Ceccarelli2Mattia Albanese3Erica Binetti4Marta Giovanetti5Massimo Ciccozzi6Fabio Scarpa7Unit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, ItalySchool of Public Health, Mount Kenya University, Thika P.O. Box 342-01000, KenyaDepartment of Public Health and Infectious Diseases, University of Rome Sapienza, 00161 Rome, ItalyDepartment of Public Health and Infectious Diseases, University of Rome Sapienza, 00161 Rome, ItalyDepartment of Public Health and Infectious Diseases, University of Rome Sapienza, 00161 Rome, ItalyDepartment of Science and Technologies for Sustainable Development and One Health, Università Campus Bio-Medico di Roma, 00128 Rome, ItalyUnit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, ItalyDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, ItalyNeglected tropical diseases (NTDs) represent a group of chronic and debilitating infections that affect more than one billion people, predominantly in low-income communities with limited health infrastructure. This paper analyzes the factors that perpetuate the burden of NTDs, highlighting how poor health infrastructure, unfavorable socioeconomic conditions and lack of therapeutic resources exacerbate their impact. The effectiveness of current interventions, such as mass drug administration (MDA) programs and improved sanitation, in reducing disease prevalence is examined. In addition, the role of climate change, which alters transmission dynamics and expands affected territories, is discussed as an emerging challenge. The analysis suggests that integrated, multisectoral approaches, including health education and infrastructure interventions, are essential to breaking the cycle of poverty and disease. Although international programs have marked significant progress, achieving elimination targets by 2030 requires sustained commitment, innovation, and increased research capacity in endemic countries.https://www.mdpi.com/1999-4915/17/1/29neglected tropical diseasesmass drug administrationhealth infrastructuresocioeconomic impactdisease burdenclimate change
spellingShingle Francesco Branda
Abdisalam Yusuf Ali
Giancarlo Ceccarelli
Mattia Albanese
Erica Binetti
Marta Giovanetti
Massimo Ciccozzi
Fabio Scarpa
Assessing the Burden of Neglected Tropical Diseases in Low-Income Communities: Challenges and Solutions
Viruses
neglected tropical diseases
mass drug administration
health infrastructure
socioeconomic impact
disease burden
climate change
title Assessing the Burden of Neglected Tropical Diseases in Low-Income Communities: Challenges and Solutions
title_full Assessing the Burden of Neglected Tropical Diseases in Low-Income Communities: Challenges and Solutions
title_fullStr Assessing the Burden of Neglected Tropical Diseases in Low-Income Communities: Challenges and Solutions
title_full_unstemmed Assessing the Burden of Neglected Tropical Diseases in Low-Income Communities: Challenges and Solutions
title_short Assessing the Burden of Neglected Tropical Diseases in Low-Income Communities: Challenges and Solutions
title_sort assessing the burden of neglected tropical diseases in low income communities challenges and solutions
topic neglected tropical diseases
mass drug administration
health infrastructure
socioeconomic impact
disease burden
climate change
url https://www.mdpi.com/1999-4915/17/1/29
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