POU2F1 inhibits miR-29b1/a cluster-mediated suppression of PIK3R1 and PIK3R3 expression to regulate gastric cancer cell invasion and migration

POU2F1 inhibits miR-29b1/a cluster-mediated suppression of PIK3R1 and PIK3R3 expression to regulate gastric cancer cell invasion and migration

Abstract. Background:. The transcription factor POU2F1 regulates the expression levels of microRNAs in neoplasia. However, the miR-29b1/a cluster modulated by POU2F1 in gastric cancer (GC) remains unknown. Methods:. Gene expression in GC cells was evaluated using reverse-transcription polymerase ch...

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Main Authors: Yizhi Xiao, Ping Yang, Wushuang Xiao, Zhen Yu, Jiaying Li, Xiaofeng Li, Jianjiao Lin, Jieming Zhang, Miaomiao Pei, Linjie Hong, Juanying Yang, Zhizhao Lin, Ping Jiang, Li Xiang, Guoxin Li, Xinbo Ai, Weiyu Dai, Weimei Tang, Jide Wang, Yanjie Yin
Format: Article
Language:English
Published: Wolters Kluwer 2025-04-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000003181
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