Prolactin Rescues Immature B-Cells from Apoptosis Induced by B-Cell Receptor Cross-Linking
Prolactin has an immunomodulatory effect and has been associated with B-cell-triggered autoimmune diseases, such as systemic lupus erythematosus (SLE). In mice that develop SLE, the PRL receptor is expressed in early bone marrow B-cells, and increased levels of PRL hasten disease manifestations, whi...
Saved in:
| Main Authors: | Rocio Flores-Fernández, Francisco Blanco-Favela, Ezequiel M. Fuentes-Pananá, Luis Chávez-Sánchez, Patricia Gorocica-Rosete, Alberto Pizaña-Venegas, Adriana Karina Chávez-Rueda |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2016/3219017 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Prolactin Increases the Frequency of Follicular T Helper Cells with Enhanced IL21 Secretion and OX40 Expression in Lupus-Prone MRL/lpr Mice
by: Yolanda P. Alemán-García, et al.
Published: (2021-01-01) -
Prolactin induces apoptosis of lactotropes in female rodents.
by: Jimena Ferraris, et al.
Published: (2014-01-01) -
A Novel Molecular Complex Expressed on Immature B Cells: A Possible Role in T Cell-IndependentB Cell Development
by: Philip J. Griebel, et al.
Published: (1996-01-01) -
The Role of Cumulus Cells for The Immature Oocyte Undergoing In Vitro Maturation Rescue: A Retrospective Analysis
by: Yudha Sudewo, et al.
Published: (2025-04-01) -
Expression of the B-cell receptor component CD79a on immature myeloid cells contributes to their tumor promoting effects.
by: Dror Luger, et al.
Published: (2013-01-01)