LncRNA APTR amplification serves as a potential glioma biomarker and promotes glioma progression via miR-6734-5p/ TCF7/LEF1 axis

LncRNA APTR amplification serves as a potential glioma biomarker and promotes glioma progression via miR-6734-5p/ TCF7/LEF1 axis

Background: Alu-mediated p21 transcriptional regulator (APTR) overexpression is detected in different human cancers; however, few reports have investigated APTR gene amplification conditions. Furthermore, whether APTR amplification is related to glioma malignancy and the underlying mechanism remain...

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Bibliographic Details
Main Authors: Heng Chen, Mengzhen Huang, Jiayi Li, Shanshan Zhang, Cuiyun Sun, Wenjun Luo, Lin Yu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-06-01
Series:Non-coding RNA Research
Subjects:
APTR
Amplification
ceRNA
Glioma
Prognostic biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054025000290
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