GENETIC FOUNDATIONS OF THE BRONCHIAL ASTHMA
The article overviews the results of the studies of the genetic foundations of predisposition to the bronchial asthma. The authors provide detailed information on the molecular and genetic mechanisms of the bronchial asthma, roles performed by the polymorphisms of the interleukin genes and their rec...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Union of pediatricians of Russia
2008-07-01
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| Series: | Педиатрическая фармакология |
| Online Access: | https://www.pedpharma.ru/jour/article/view/831 |
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| _version_ | 1849394049459421184 |
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| author | A.Yu. Asanov L.S. Namazova V.G. Pinelis N.V. Zhurkova N.I. Voznesenskaya |
| author_facet | A.Yu. Asanov L.S. Namazova V.G. Pinelis N.V. Zhurkova N.I. Voznesenskaya |
| author_sort | A.Yu. Asanov |
| collection | DOAJ |
| description | The article overviews the results of the studies of the genetic foundations of predisposition to the bronchial asthma. The authors provide detailed information on the molecular and genetic mechanisms of the bronchial asthma, roles performed by the polymorphisms of the interleukin genes and their receptors, IgE receptors, adrenergic receptors, CYS-LT enzymes in the pathogenesis of this disease, as well as their impact on the effectiveness of the drug therapy.Key words: bronchial asthma, genetic predisposition, pharmacogenetics. |
| format | Article |
| id | doaj-art-5bd98d9693ab49c7a8b74c21bd128e82 |
| institution | Kabale University |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2008-07-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-5bd98d9693ab49c7a8b74c21bd128e822025-08-20T03:40:11ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892008-07-01543137826GENETIC FOUNDATIONS OF THE BRONCHIAL ASTHMAA.Yu. Asanov0L.S. Namazova1V.G. Pinelis2N.V. Zhurkova3N.I. Voznesenskaya4Scientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowThe article overviews the results of the studies of the genetic foundations of predisposition to the bronchial asthma. The authors provide detailed information on the molecular and genetic mechanisms of the bronchial asthma, roles performed by the polymorphisms of the interleukin genes and their receptors, IgE receptors, adrenergic receptors, CYS-LT enzymes in the pathogenesis of this disease, as well as their impact on the effectiveness of the drug therapy.Key words: bronchial asthma, genetic predisposition, pharmacogenetics.https://www.pedpharma.ru/jour/article/view/831 |
| spellingShingle | A.Yu. Asanov L.S. Namazova V.G. Pinelis N.V. Zhurkova N.I. Voznesenskaya GENETIC FOUNDATIONS OF THE BRONCHIAL ASTHMA Педиатрическая фармакология |
| title | GENETIC FOUNDATIONS OF THE BRONCHIAL ASTHMA |
| title_full | GENETIC FOUNDATIONS OF THE BRONCHIAL ASTHMA |
| title_fullStr | GENETIC FOUNDATIONS OF THE BRONCHIAL ASTHMA |
| title_full_unstemmed | GENETIC FOUNDATIONS OF THE BRONCHIAL ASTHMA |
| title_short | GENETIC FOUNDATIONS OF THE BRONCHIAL ASTHMA |
| title_sort | genetic foundations of the bronchial asthma |
| url | https://www.pedpharma.ru/jour/article/view/831 |
| work_keys_str_mv | AT ayuasanov geneticfoundationsofthebronchialasthma AT lsnamazova geneticfoundationsofthebronchialasthma AT vgpinelis geneticfoundationsofthebronchialasthma AT nvzhurkova geneticfoundationsofthebronchialasthma AT nivoznesenskaya geneticfoundationsofthebronchialasthma |