Point of care ultrasonography of quadriceps femoris muscle thickness for assessing nutritional status in critically ill children

Abstract Muscle wasting occurs early during critical illness. It is associated with poor PICU outcomes. Ultrasonography can detect muscle thickness in critically ill children. Study quadriceps muscle thickness to assess the nutritional status on admission and follow the muscle thickness change throu...

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Main Authors: Shereen A. Mohamed, Hanan M. Elsawy, Hafez M. Bazaraa, Mohamed H. Ghobashy, Mohamed Abdallah Abd El Megied
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-01205-w
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author Shereen A. Mohamed
Hanan M. Elsawy
Hafez M. Bazaraa
Mohamed H. Ghobashy
Mohamed Abdallah Abd El Megied
author_facet Shereen A. Mohamed
Hanan M. Elsawy
Hafez M. Bazaraa
Mohamed H. Ghobashy
Mohamed Abdallah Abd El Megied
author_sort Shereen A. Mohamed
collection DOAJ
description Abstract Muscle wasting occurs early during critical illness. It is associated with poor PICU outcomes. Ultrasonography can detect muscle thickness in critically ill children. Study quadriceps muscle thickness to assess the nutritional status on admission and follow the muscle thickness change throughout the first week of admission in PICU using point-of-care ultrasonography. This cohort study was conducted on 55 critically ill mechanically ventilated children aged between 2 months and 14 years. Serial measurements of quadriceps muscle thickness were done by ultrasound, during the first week of admission. Quadriceps muscle thickness decreased by 16.4% over the 1st week of admission. The muscle wasting was significantly correlated with STRONGkids score, the inability to achieve target caloric requirements during the 1st week of admission, duration of ventilation, PRISM score, and mortality. Point of care ultrasonography is an easy tool for assessing PICU muscle wasting. Loss of muscle mass during the first week of PICU admission is correlated to mortality, thus it can be utilized in predicting PICU outcomes.
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spelling doaj-art-5bcf11856f27431da26000cfa70cabda2025-08-20T03:10:13ZengNature PortfolioScientific Reports2045-23222025-05-0115111110.1038/s41598-025-01205-wPoint of care ultrasonography of quadriceps femoris muscle thickness for assessing nutritional status in critically ill childrenShereen A. Mohamed0Hanan M. Elsawy1Hafez M. Bazaraa2Mohamed H. Ghobashy3Mohamed Abdallah Abd El Megied4Department of Pediatrics, Faculty of Medicine, Cairo UniversityDepartment of Pediatrics, Faculty of Medicine, Cairo UniversityDepartment of Pediatrics, Faculty of Medicine, Cairo UniversityDepartment of Radiology, Faculty of Medicine, Cairo UniversityDepartment of Pediatrics, Faculty of Medicine, Cairo UniversityAbstract Muscle wasting occurs early during critical illness. It is associated with poor PICU outcomes. Ultrasonography can detect muscle thickness in critically ill children. Study quadriceps muscle thickness to assess the nutritional status on admission and follow the muscle thickness change throughout the first week of admission in PICU using point-of-care ultrasonography. This cohort study was conducted on 55 critically ill mechanically ventilated children aged between 2 months and 14 years. Serial measurements of quadriceps muscle thickness were done by ultrasound, during the first week of admission. Quadriceps muscle thickness decreased by 16.4% over the 1st week of admission. The muscle wasting was significantly correlated with STRONGkids score, the inability to achieve target caloric requirements during the 1st week of admission, duration of ventilation, PRISM score, and mortality. Point of care ultrasonography is an easy tool for assessing PICU muscle wasting. Loss of muscle mass during the first week of PICU admission is correlated to mortality, thus it can be utilized in predicting PICU outcomes.https://doi.org/10.1038/s41598-025-01205-wQuadricepsUltrasonographyCritically illMortality
spellingShingle Shereen A. Mohamed
Hanan M. Elsawy
Hafez M. Bazaraa
Mohamed H. Ghobashy
Mohamed Abdallah Abd El Megied
Point of care ultrasonography of quadriceps femoris muscle thickness for assessing nutritional status in critically ill children
Scientific Reports
Quadriceps
Ultrasonography
Critically ill
Mortality
title Point of care ultrasonography of quadriceps femoris muscle thickness for assessing nutritional status in critically ill children
title_full Point of care ultrasonography of quadriceps femoris muscle thickness for assessing nutritional status in critically ill children
title_fullStr Point of care ultrasonography of quadriceps femoris muscle thickness for assessing nutritional status in critically ill children
title_full_unstemmed Point of care ultrasonography of quadriceps femoris muscle thickness for assessing nutritional status in critically ill children
title_short Point of care ultrasonography of quadriceps femoris muscle thickness for assessing nutritional status in critically ill children
title_sort point of care ultrasonography of quadriceps femoris muscle thickness for assessing nutritional status in critically ill children
topic Quadriceps
Ultrasonography
Critically ill
Mortality
url https://doi.org/10.1038/s41598-025-01205-w
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