Renal Dysfunction in a Patient With Crohn's Disease During Ustekinumab Treatment: A Case Report and Review of the Literature

ABSTRACT: Ustekinumab is a first-line drug for Crohn's disease. However, little is known about its potential adverse effects on renal function. We present the case of a 42-year-old man with Crohn's disease who developed chronic renal dysfunction during ustekinumab treatment, which resolved...

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Main Authors: Yuge Wei, Ms, Gechong Ruan, MD, Yan Qin, MD, Xiaoyin Bai, MD, Hong Yang, MD
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Therapeutic Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X24000237
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Summary:ABSTRACT: Ustekinumab is a first-line drug for Crohn's disease. However, little is known about its potential adverse effects on renal function. We present the case of a 42-year-old man with Crohn's disease who developed chronic renal dysfunction during ustekinumab treatment, which resolved after discontinuing ustekinumab. The findings underscore the importance of close monitoring of renal function in patients receiving ustekinumab, particularly those with preexisting kidney disease or risk factors for renal dysfunction.
ISSN:0011-393X