Effectiveness of Carbon Localization for Invasive Breast Cancer: An Institutional Experience
Introduction. The final oncological and aesthetic results of breast-conserving surgery (BCS) are influenced by the precise localization of breast cancer (BC) tumors and by the quality of the intraoperative margin assessment technique. This study aimed to assess the effectiveness of the carbon locali...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | The Breast Journal |
| Online Access: | http://dx.doi.org/10.1155/2023/4082501 |
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| author | Etienne El-Helou Christine Eddy Simona Picchia Carine Van de Merckt Magali Radermeker Michel Moreau Filip De Neubourg Denis Larsimont Isabelle Veys C. Florin Pop |
| author_facet | Etienne El-Helou Christine Eddy Simona Picchia Carine Van de Merckt Magali Radermeker Michel Moreau Filip De Neubourg Denis Larsimont Isabelle Veys C. Florin Pop |
| author_sort | Etienne El-Helou |
| collection | DOAJ |
| description | Introduction. The final oncological and aesthetic results of breast-conserving surgery (BCS) are influenced by the precise localization of breast cancer (BC) tumors and by the quality of the intraoperative margin assessment technique. This study aimed to assess the effectiveness of the carbon localization (CL) technique by determining the success rate of BC identification and the proportion of adequate complete resection of BC lesions. Methods. We conducted a cross-sectional retrospective study of patients treated with primary BCS for invasive BC who underwent CL of their BC lesion at the Jules Bordet Institute between January 2015 and December 2017. Descriptive statistics with categorical and continuous variables were used. The success rate of tumor identification and the rate of adequate excision were calculated using the test of percentages for independent dichotomous data. Results. This study included 542 patients with 564 nonpalpable BC lesions. The median pathological tumor size was 12 mm. Of these, 460 were invasive ductal carcinomas. Most of the tumors were of the luminal subtype. CL was performed using ultrasound guidance in 98.5% of cases. The median delay between CL and surgery was 5 days, with 46% of the patients having CL one day before surgery. The lumpectomy weighed 38 g on average, with a median diameter of the surgical sample at 6 cm and a median volume of 44 cm3 (6–369). One-stage complete resection was successfully performed in 93.4% of cases. In 36% of cases, an intraoperative re-excision was performed, based on intraoperative macroscopic pathological margin evaluation. The tumor was identified in 98.9% of cases in the breast surgical specimen. Conclusion. This study demonstrated high success rates for BC tumor identification (99%) and one-stage complete resection (93.4%) after BCS and CL. These results show that CL is an effective, simple, and inexpensive localization technique for successful excision of BC lesions during BCS. |
| format | Article |
| id | doaj-art-5bcb9d05abe846b8b3778de1cdc5f83d |
| institution | OA Journals |
| issn | 1524-4741 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Breast Journal |
| spelling | doaj-art-5bcb9d05abe846b8b3778de1cdc5f83d2025-08-20T02:05:14ZengWileyThe Breast Journal1524-47412023-01-01202310.1155/2023/4082501Effectiveness of Carbon Localization for Invasive Breast Cancer: An Institutional ExperienceEtienne El-Helou0Christine Eddy1Simona Picchia2Carine Van de Merckt3Magali Radermeker4Michel Moreau5Filip De Neubourg6Denis Larsimont7Isabelle Veys8C. Florin Pop9Department of SurgeryDepartment of SurgeryDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyData Centre and Statistic DepartmentDepartment of SurgeryDepartment of PathologyDepartment of SurgeryDepartment of SurgeryIntroduction. The final oncological and aesthetic results of breast-conserving surgery (BCS) are influenced by the precise localization of breast cancer (BC) tumors and by the quality of the intraoperative margin assessment technique. This study aimed to assess the effectiveness of the carbon localization (CL) technique by determining the success rate of BC identification and the proportion of adequate complete resection of BC lesions. Methods. We conducted a cross-sectional retrospective study of patients treated with primary BCS for invasive BC who underwent CL of their BC lesion at the Jules Bordet Institute between January 2015 and December 2017. Descriptive statistics with categorical and continuous variables were used. The success rate of tumor identification and the rate of adequate excision were calculated using the test of percentages for independent dichotomous data. Results. This study included 542 patients with 564 nonpalpable BC lesions. The median pathological tumor size was 12 mm. Of these, 460 were invasive ductal carcinomas. Most of the tumors were of the luminal subtype. CL was performed using ultrasound guidance in 98.5% of cases. The median delay between CL and surgery was 5 days, with 46% of the patients having CL one day before surgery. The lumpectomy weighed 38 g on average, with a median diameter of the surgical sample at 6 cm and a median volume of 44 cm3 (6–369). One-stage complete resection was successfully performed in 93.4% of cases. In 36% of cases, an intraoperative re-excision was performed, based on intraoperative macroscopic pathological margin evaluation. The tumor was identified in 98.9% of cases in the breast surgical specimen. Conclusion. This study demonstrated high success rates for BC tumor identification (99%) and one-stage complete resection (93.4%) after BCS and CL. These results show that CL is an effective, simple, and inexpensive localization technique for successful excision of BC lesions during BCS.http://dx.doi.org/10.1155/2023/4082501 |
| spellingShingle | Etienne El-Helou Christine Eddy Simona Picchia Carine Van de Merckt Magali Radermeker Michel Moreau Filip De Neubourg Denis Larsimont Isabelle Veys C. Florin Pop Effectiveness of Carbon Localization for Invasive Breast Cancer: An Institutional Experience The Breast Journal |
| title | Effectiveness of Carbon Localization for Invasive Breast Cancer: An Institutional Experience |
| title_full | Effectiveness of Carbon Localization for Invasive Breast Cancer: An Institutional Experience |
| title_fullStr | Effectiveness of Carbon Localization for Invasive Breast Cancer: An Institutional Experience |
| title_full_unstemmed | Effectiveness of Carbon Localization for Invasive Breast Cancer: An Institutional Experience |
| title_short | Effectiveness of Carbon Localization for Invasive Breast Cancer: An Institutional Experience |
| title_sort | effectiveness of carbon localization for invasive breast cancer an institutional experience |
| url | http://dx.doi.org/10.1155/2023/4082501 |
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