Acute Abdomen in a Patient with Cancer Pain on Oxycodone
Opioids are a mainstay of treatment for moderate to severe cancer pain. At present, oxycodone has fewer adverse effects compared to morphine and is widely used for cancer pain therapy. The adverse effects of oxycodone are similar to morphine and include constipation, nausea, and sedation. However, a...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/858672 |
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| author | Naomi Kishine Atsunobu Tsunoda Seiji Kishimoto Tomohisa Shoko |
| author_facet | Naomi Kishine Atsunobu Tsunoda Seiji Kishimoto Tomohisa Shoko |
| author_sort | Naomi Kishine |
| collection | DOAJ |
| description | Opioids are a mainstay of treatment for moderate to severe cancer pain. At present, oxycodone has fewer adverse effects compared to morphine and is widely used for cancer pain therapy. The adverse effects of oxycodone are similar to morphine and include constipation, nausea, and sedation. However, acute abdominal pain is rarely seen. Here, we describe a cancer patient presenting with acute abdomen with stercoral diarrhea. A 54-year-old man with squamous cell carcinoma of the external auditory canal had been taking oxycodone for pain relief. The patient had taken oxycodone for several months and had never complained of either diarrhea or constipation. After an increase in the dosage of oxycodone, he complained of abdominal distension and constipation. After being administered a laxative, he complained of diarrhea and severe abdominal pain. He visited the emergency department and was diagnosed with acute colonic obstruction caused by severe constipation. He self-medicated with oxycodone at dosages of up to 180 mg/day, and this abrupt increase of oxycodone caused stercoral diarrhea. Finally, total blockage of stool developed, resulting in acute abdomen. |
| format | Article |
| id | doaj-art-5bca8c3fb3254068910a604d0dafac4d |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-5bca8c3fb3254068910a604d0dafac4d2025-08-20T02:05:13ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/858672858672Acute Abdomen in a Patient with Cancer Pain on OxycodoneNaomi Kishine0Atsunobu Tsunoda1Seiji Kishimoto2Tomohisa Shoko3Department of Otolaryngology, Tokyo Medical and Dental University, Tokyo 113-8519, JapanDepartment of Otolaryngology, Tokyo Medical and Dental University, Tokyo 113-8519, JapanHead and Neck Surgery, Tokyo Medical and Dental University, Tokyo 113-8519, JapanER Center, Tokyo Medical and Dental University, Tokyo 113-8519, JapanOpioids are a mainstay of treatment for moderate to severe cancer pain. At present, oxycodone has fewer adverse effects compared to morphine and is widely used for cancer pain therapy. The adverse effects of oxycodone are similar to morphine and include constipation, nausea, and sedation. However, acute abdominal pain is rarely seen. Here, we describe a cancer patient presenting with acute abdomen with stercoral diarrhea. A 54-year-old man with squamous cell carcinoma of the external auditory canal had been taking oxycodone for pain relief. The patient had taken oxycodone for several months and had never complained of either diarrhea or constipation. After an increase in the dosage of oxycodone, he complained of abdominal distension and constipation. After being administered a laxative, he complained of diarrhea and severe abdominal pain. He visited the emergency department and was diagnosed with acute colonic obstruction caused by severe constipation. He self-medicated with oxycodone at dosages of up to 180 mg/day, and this abrupt increase of oxycodone caused stercoral diarrhea. Finally, total blockage of stool developed, resulting in acute abdomen.http://dx.doi.org/10.1155/2011/858672 |
| spellingShingle | Naomi Kishine Atsunobu Tsunoda Seiji Kishimoto Tomohisa Shoko Acute Abdomen in a Patient with Cancer Pain on Oxycodone Case Reports in Medicine |
| title | Acute Abdomen in a Patient with Cancer Pain on Oxycodone |
| title_full | Acute Abdomen in a Patient with Cancer Pain on Oxycodone |
| title_fullStr | Acute Abdomen in a Patient with Cancer Pain on Oxycodone |
| title_full_unstemmed | Acute Abdomen in a Patient with Cancer Pain on Oxycodone |
| title_short | Acute Abdomen in a Patient with Cancer Pain on Oxycodone |
| title_sort | acute abdomen in a patient with cancer pain on oxycodone |
| url | http://dx.doi.org/10.1155/2011/858672 |
| work_keys_str_mv | AT naomikishine acuteabdomeninapatientwithcancerpainonoxycodone AT atsunobutsunoda acuteabdomeninapatientwithcancerpainonoxycodone AT seijikishimoto acuteabdomeninapatientwithcancerpainonoxycodone AT tomohisashoko acuteabdomeninapatientwithcancerpainonoxycodone |