Advances in SPECT for Optimizing the Liver Tumors Radioembolization Using Yttrium-90 Microspheres

Radioembolization (RE) with Yttrium-90 ( 90 Y) microspheres is an effective treatment for unresectable liver tumors. The activity of the microspheres to be administered should be calculated based on the type of microspheres. Technetium-99m macroaggregated albumin ( 99m Tc-MAA) single photon emission...

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Bibliographic Details
Main Authors: Hoda Roshan, Ahmadreza Azarm, Babak Mahmoudian, Jalil Islamian
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2015-04-01
Series:World Journal of Nuclear Medicine
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.157120
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Summary:Radioembolization (RE) with Yttrium-90 ( 90 Y) microspheres is an effective treatment for unresectable liver tumors. The activity of the microspheres to be administered should be calculated based on the type of microspheres. Technetium-99m macroaggregated albumin ( 99m Tc-MAA) single photon emission computed tomography/computed tomography (SPECT/CT) is a reliable assessment before RE to ensure the safe delivery of microspheres into the target. 90 Y bremsstrahlung SPECT imaging as a posttherapeutic assessment approach enables the reliable determination of absorbed dose, which is indispensable for the verification of treatment efficacy. This article intends to provide a review of the methods of optimizing 90 Y bremsstrahlung SPECT imaging to improve the treatment efficacy of liver tumor RE using 90 Y microspheres.
ISSN:1450-1147
1607-3312