Is laser-assisted hatching better than mechanical method for enhancing pregnancy rate in frozen-thawed blastocyst transfer cycles?

Objective: To investigate the effect of laser-assisted hatching (LAH) compared with mechanical-assisted hatching (MAH) for enhancing clinical outcomes in frozen-thawed blastocysts (FTBs) transfer cycles. Materials and Methods: The culture of all pronucleate embryos to the blastocyst stage and the se...

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Bibliographic Details
Main Authors: Y. J. Lee, S. C. Kim, J. K. Joo, H. G. Kim, G. R. Ko, C. W. Kim, K. S. Lee
Format: Article
Language:English
Published: IMR Press 2020-02-01
Series:Clinical and Experimental Obstetrics & Gynecology
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Online Access:https://www.imrpress.com/journal/CEOG/47/1/10.31083/j.ceog.2020.01.5023
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Summary:Objective: To investigate the effect of laser-assisted hatching (LAH) compared with mechanical-assisted hatching (MAH) for enhancing clinical outcomes in frozen-thawed blastocysts (FTBs) transfer cycles. Materials and Methods: The culture of all pronucleate embryos to the blastocyst stage and the selection of blastocysts ≥ grade 3BB (Gardner and Schooleraft score), followed by FTBs transfer cycles with LAH (n=105) or with MAH (n=101). Clinical outcomes including clinical and ongoing pregnancy rates were investigated.Results: There were no significant differences in clinical and ongoing pregnancy rates between LAH and MAH groups in FTBs transfer cycles. Conclusion: LAH does not improve pregnancy outcomes significantly compared to MAH in FTBs transfer cycles.
ISSN:0390-6663