Deterministic, stochastic and fractional mathematical approaches applied to AMR

In this work, we study the qualitative properties of a simple mathematical model that can be applied to the reversal of antimicrobial resistance. In particular, we analyze the model from three perspectives: ordinary differential equations (ODEs), stochastic differential equations (SDEs) driven by Br...

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Main Authors: Sebastian Builes, Jhoana P. Romero-Leiton, Leon A. Valencia
Format: Article
Language:English
Published: AIMS Press 2025-02-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2025015
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author Sebastian Builes
Jhoana P. Romero-Leiton
Leon A. Valencia
author_facet Sebastian Builes
Jhoana P. Romero-Leiton
Leon A. Valencia
author_sort Sebastian Builes
collection DOAJ
description In this work, we study the qualitative properties of a simple mathematical model that can be applied to the reversal of antimicrobial resistance. In particular, we analyze the model from three perspectives: ordinary differential equations (ODEs), stochastic differential equations (SDEs) driven by Brownian motion, and fractional differential equations (FDEs) with Caputo temporal derivatives. Finally, we address the case of Escherichia coli exposed to colistin using parameters from the literature in order to assess the validity of the qualitative properties of the model.
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spelling doaj-art-5bba7aadc865462fb663da9c5d3edb5a2025-08-20T01:54:34ZengAIMS PressMathematical Biosciences and Engineering1551-00182025-02-0122238941410.3934/mbe.2025015Deterministic, stochastic and fractional mathematical approaches applied to AMRSebastian Builes0Jhoana P. Romero-Leiton1Leon A. Valencia2Institute of Mathematics, University of Antioquia, Medellin, ColombiaDepartment of Mathematical Sciences, University of Puerto Rico at Mayagüez, Puerto Rico, USAInstitute of Mathematics, University of Antioquia, Medellin, ColombiaIn this work, we study the qualitative properties of a simple mathematical model that can be applied to the reversal of antimicrobial resistance. In particular, we analyze the model from three perspectives: ordinary differential equations (ODEs), stochastic differential equations (SDEs) driven by Brownian motion, and fractional differential equations (FDEs) with Caputo temporal derivatives. Finally, we address the case of Escherichia coli exposed to colistin using parameters from the literature in order to assess the validity of the qualitative properties of the model.https://www.aimspress.com/article/doi/10.3934/mbe.2025015ordinary differential equationstochastic differential equationfractional differential equationcaputo derivativebrownian motionstabilityqualitative properties
spellingShingle Sebastian Builes
Jhoana P. Romero-Leiton
Leon A. Valencia
Deterministic, stochastic and fractional mathematical approaches applied to AMR
Mathematical Biosciences and Engineering
ordinary differential equation
stochastic differential equation
fractional differential equation
caputo derivative
brownian motion
stability
qualitative properties
title Deterministic, stochastic and fractional mathematical approaches applied to AMR
title_full Deterministic, stochastic and fractional mathematical approaches applied to AMR
title_fullStr Deterministic, stochastic and fractional mathematical approaches applied to AMR
title_full_unstemmed Deterministic, stochastic and fractional mathematical approaches applied to AMR
title_short Deterministic, stochastic and fractional mathematical approaches applied to AMR
title_sort deterministic stochastic and fractional mathematical approaches applied to amr
topic ordinary differential equation
stochastic differential equation
fractional differential equation
caputo derivative
brownian motion
stability
qualitative properties
url https://www.aimspress.com/article/doi/10.3934/mbe.2025015
work_keys_str_mv AT sebastianbuiles deterministicstochasticandfractionalmathematicalapproachesappliedtoamr
AT jhoanapromeroleiton deterministicstochasticandfractionalmathematicalapproachesappliedtoamr
AT leonavalencia deterministicstochasticandfractionalmathematicalapproachesappliedtoamr