National prevalence and incidence of benign prostatic hyperplasia/lower urinary tract symptoms and validated risk factors pattern

Background To date, limited research has been conducted within China to elucidate the national prevalence and incidence rates of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS). Additionally, there is a scarcity of studies that have systematically investigated the reliable risk...

Full description

Saved in:
Bibliographic Details
Main Authors: Lede Lin, Wei Wang, Yanxiang Shao, Xiang Li, Liang Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:The Aging Male
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/13685538.2025.2478875
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850109072718692352
author Lede Lin
Wei Wang
Yanxiang Shao
Xiang Li
Liang Zhou
author_facet Lede Lin
Wei Wang
Yanxiang Shao
Xiang Li
Liang Zhou
author_sort Lede Lin
collection DOAJ
description Background To date, limited research has been conducted within China to elucidate the national prevalence and incidence rates of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS). Additionally, there is a scarcity of studies that have systematically investigated the reliable risk factor patterns associated with the development of BPH/LUTS among the Chinese population.Methods The study was in both cross-sectional and prospective cohort study design. The participants were derived from the China Health and Retirement Longitudinal Study (CHARLS). National prevalence and incidence of BPH/LUTS, average onset age of BPH/LUTS, medication rate of BPH/LUTS, and validated risk factors pattern of BPH/LUTS in the Chinese population were investigated.Results The overall prevalence and annual incidence of BPH/LUTS were 11.10% and 2.23%. In China, the male population affected by BPH/LUTS typically presented at an average age of 55–65 years. However, the medication rate was merely more than 30%. After conducting univariate and multivariate logistic regression analysis in both cross-sectional and prospective cohort study designs, we observed that dyslipidemia was the most stable risk factor of BPH/LUTS occurrence in three adjusted models (OR [95% CI]: 2.41 [1.37–4.25]; 2.05 [1.10–3.81] and 2.40 [1.19–4.84], respectively).Conclusions This is the first study to delineate the prevalence and incidence of BPH/LUTS in Chinese, at the national level. The study reminded us that it was dyslipidemia rather than other chronic diseases or bad habits that posed a detrimental influence on BPH/LUTS occurrence in Chinese. Our data would facilitate the disease’s early screening and medical policy formulation.
format Article
id doaj-art-5bb326469f4545bab7cf5080b6f9d147
institution OA Journals
issn 1368-5538
1473-0790
language English
publishDate 2025-12-01
publisher Taylor & Francis Group
record_format Article
series The Aging Male
spelling doaj-art-5bb326469f4545bab7cf5080b6f9d1472025-08-20T02:38:11ZengTaylor & Francis GroupThe Aging Male1368-55381473-07902025-12-0128110.1080/13685538.2025.2478875National prevalence and incidence of benign prostatic hyperplasia/lower urinary tract symptoms and validated risk factors patternLede Lin0Wei Wang1Yanxiang Shao2Xiang Li3Liang Zhou4Department of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, ChinaBackground To date, limited research has been conducted within China to elucidate the national prevalence and incidence rates of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS). Additionally, there is a scarcity of studies that have systematically investigated the reliable risk factor patterns associated with the development of BPH/LUTS among the Chinese population.Methods The study was in both cross-sectional and prospective cohort study design. The participants were derived from the China Health and Retirement Longitudinal Study (CHARLS). National prevalence and incidence of BPH/LUTS, average onset age of BPH/LUTS, medication rate of BPH/LUTS, and validated risk factors pattern of BPH/LUTS in the Chinese population were investigated.Results The overall prevalence and annual incidence of BPH/LUTS were 11.10% and 2.23%. In China, the male population affected by BPH/LUTS typically presented at an average age of 55–65 years. However, the medication rate was merely more than 30%. After conducting univariate and multivariate logistic regression analysis in both cross-sectional and prospective cohort study designs, we observed that dyslipidemia was the most stable risk factor of BPH/LUTS occurrence in three adjusted models (OR [95% CI]: 2.41 [1.37–4.25]; 2.05 [1.10–3.81] and 2.40 [1.19–4.84], respectively).Conclusions This is the first study to delineate the prevalence and incidence of BPH/LUTS in Chinese, at the national level. The study reminded us that it was dyslipidemia rather than other chronic diseases or bad habits that posed a detrimental influence on BPH/LUTS occurrence in Chinese. Our data would facilitate the disease’s early screening and medical policy formulation.https://www.tandfonline.com/doi/10.1080/13685538.2025.2478875PrevalenceincidenceBPH/LUTSrisk factors patternChinese
spellingShingle Lede Lin
Wei Wang
Yanxiang Shao
Xiang Li
Liang Zhou
National prevalence and incidence of benign prostatic hyperplasia/lower urinary tract symptoms and validated risk factors pattern
The Aging Male
Prevalence
incidence
BPH/LUTS
risk factors pattern
Chinese
title National prevalence and incidence of benign prostatic hyperplasia/lower urinary tract symptoms and validated risk factors pattern
title_full National prevalence and incidence of benign prostatic hyperplasia/lower urinary tract symptoms and validated risk factors pattern
title_fullStr National prevalence and incidence of benign prostatic hyperplasia/lower urinary tract symptoms and validated risk factors pattern
title_full_unstemmed National prevalence and incidence of benign prostatic hyperplasia/lower urinary tract symptoms and validated risk factors pattern
title_short National prevalence and incidence of benign prostatic hyperplasia/lower urinary tract symptoms and validated risk factors pattern
title_sort national prevalence and incidence of benign prostatic hyperplasia lower urinary tract symptoms and validated risk factors pattern
topic Prevalence
incidence
BPH/LUTS
risk factors pattern
Chinese
url https://www.tandfonline.com/doi/10.1080/13685538.2025.2478875
work_keys_str_mv AT ledelin nationalprevalenceandincidenceofbenignprostatichyperplasialowerurinarytractsymptomsandvalidatedriskfactorspattern
AT weiwang nationalprevalenceandincidenceofbenignprostatichyperplasialowerurinarytractsymptomsandvalidatedriskfactorspattern
AT yanxiangshao nationalprevalenceandincidenceofbenignprostatichyperplasialowerurinarytractsymptomsandvalidatedriskfactorspattern
AT xiangli nationalprevalenceandincidenceofbenignprostatichyperplasialowerurinarytractsymptomsandvalidatedriskfactorspattern
AT liangzhou nationalprevalenceandincidenceofbenignprostatichyperplasialowerurinarytractsymptomsandvalidatedriskfactorspattern