Hyperuricemic Renal Failure in Nonhematologic Solid Tumors: A Case Report and Review of the Literature
Tumor lysis syndrome (TLS) is an oncologic emergency that is caused by massive tumor cell lysis. It is commonly associated with hematological cancers like leukemia and lymphoma and uncommonly with solid nonhematologic tumors as well. However, spontaneous tumor lysis syndrome (STLS) without any cytot...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/314056 |
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| author | Neeraj Saini Kyeong Pyo Lee Smita Jha Sanket Patel Neelima Bonthu Ankit Kansagra Ashmeet Bhatia Sandra E. Martinez Jaymin Patel Sarah Altamimi Sara Ghotb |
| author_facet | Neeraj Saini Kyeong Pyo Lee Smita Jha Sanket Patel Neelima Bonthu Ankit Kansagra Ashmeet Bhatia Sandra E. Martinez Jaymin Patel Sarah Altamimi Sara Ghotb |
| author_sort | Neeraj Saini |
| collection | DOAJ |
| description | Tumor lysis syndrome (TLS) is an oncologic emergency that is caused by massive tumor cell lysis. It is commonly associated with hematological cancers like leukemia and lymphoma and uncommonly with solid nonhematologic tumors as well. However, spontaneous tumor lysis syndrome (STLS) without any cytotoxic chemotherapy rarely occurs in solid tumors. We describe a case of STLS in a metastatic adenocarcinoma of unknown primary and review the literature of STLS in solid non-hematologic tumors to identify various risk factors for pathogenesis of this entity. |
| format | Article |
| id | doaj-art-5bae38bd1b724ca19b7e4d22401ee56d |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-5bae38bd1b724ca19b7e4d22401ee56d2025-08-20T02:05:16ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/314056314056Hyperuricemic Renal Failure in Nonhematologic Solid Tumors: A Case Report and Review of the LiteratureNeeraj Saini0Kyeong Pyo Lee1Smita Jha2Sanket Patel3Neelima Bonthu4Ankit Kansagra5Ashmeet Bhatia6Sandra E. Martinez7Jaymin Patel8Sarah Altamimi9Sara Ghotb10Department of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USADepartment of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USADepartment of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USADepartment of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USADepartment of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USADepartment of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USADepartment of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USADepartment of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USADepartment of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USADepartment of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USADepartment of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USATumor lysis syndrome (TLS) is an oncologic emergency that is caused by massive tumor cell lysis. It is commonly associated with hematological cancers like leukemia and lymphoma and uncommonly with solid nonhematologic tumors as well. However, spontaneous tumor lysis syndrome (STLS) without any cytotoxic chemotherapy rarely occurs in solid tumors. We describe a case of STLS in a metastatic adenocarcinoma of unknown primary and review the literature of STLS in solid non-hematologic tumors to identify various risk factors for pathogenesis of this entity.http://dx.doi.org/10.1155/2012/314056 |
| spellingShingle | Neeraj Saini Kyeong Pyo Lee Smita Jha Sanket Patel Neelima Bonthu Ankit Kansagra Ashmeet Bhatia Sandra E. Martinez Jaymin Patel Sarah Altamimi Sara Ghotb Hyperuricemic Renal Failure in Nonhematologic Solid Tumors: A Case Report and Review of the Literature Case Reports in Medicine |
| title | Hyperuricemic Renal Failure in Nonhematologic Solid Tumors: A Case Report and Review of the Literature |
| title_full | Hyperuricemic Renal Failure in Nonhematologic Solid Tumors: A Case Report and Review of the Literature |
| title_fullStr | Hyperuricemic Renal Failure in Nonhematologic Solid Tumors: A Case Report and Review of the Literature |
| title_full_unstemmed | Hyperuricemic Renal Failure in Nonhematologic Solid Tumors: A Case Report and Review of the Literature |
| title_short | Hyperuricemic Renal Failure in Nonhematologic Solid Tumors: A Case Report and Review of the Literature |
| title_sort | hyperuricemic renal failure in nonhematologic solid tumors a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2012/314056 |
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