Glossopharyngeal Neuralgia: Epidemiology, Risk factors, Pathophysiology, Differential diagnosis, and Treatment Options
# Purpose of Review This is a comprehensive review of the most recent literature on glossopharyngeal neuralgia (GPN), a relatively rare form of neuropathic facial pain. It covers the epidemiology, risk factors, pathophysiology, and differential diagnosis given that glossopharyngeal neuralgia can o...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Open Medical Publishing
2022-06-01
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| Series: | Health Psychology Research |
| Online Access: | https://doi.org/10.52965/001c.36042 |
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| _version_ | 1823857563820621824 |
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| author | Andrew Han Carver Montgomery Alexandra Zamora Emilie Winder Adam D. Kaye Caroline Carroll Alfonso Aquino Juyeon Kakazu Alan D. Kaye |
| author_facet | Andrew Han Carver Montgomery Alexandra Zamora Emilie Winder Adam D. Kaye Caroline Carroll Alfonso Aquino Juyeon Kakazu Alan D. Kaye |
| author_sort | Andrew Han |
| collection | DOAJ |
| description | # Purpose of Review
This is a comprehensive review of the most recent literature on glossopharyngeal neuralgia (GPN), a relatively rare form of neuropathic facial pain. It covers the epidemiology, risk factors, pathophysiology, and differential diagnosis given that glossopharyngeal neuralgia can often be confused with other facial pain syndromes. Finally, we extensively review recent findings regarding medical or conservative measures, minimally invasive, and surgical options for potentially treating and managing glossopharyngeal neuralgia.
# Recent Findings
An in-depth analysis of the recent literature indicates that glossopharyngeal neuralgia is not only rare but its etiology and pathophysiology are complex and are often secondary to other disease processes. Regardless, current management options are shown to be effective in controlling pain. Conservatively, first-line management of GPN is carbamazepine, but gabapentin and eslicarbazepine acetate are suitable alternatives. In terms of current minimally invasive pain management techniques, pulsed radiofrequency ablation, nerve blocks, or percutaneous radiofrequency thermocoagulation are effective. Finally, surgical management involves microvascular decompression and rhizotomy.
# Summary
While there are currently many viable options for addressing glossopharyngeal neuralgia pain ranging from conservative to surgical management, the complex nature of GPN etiology, pathophysiology, and involved anatomical structures prompts further research for more effective ways to treat the disease. |
| format | Article |
| id | doaj-art-5b8c1af5a79941479e6c4ffd5bfb4f3d |
| institution | Kabale University |
| issn | 2420-8124 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Open Medical Publishing |
| record_format | Article |
| series | Health Psychology Research |
| spelling | doaj-art-5b8c1af5a79941479e6c4ffd5bfb4f3d2025-02-11T20:30:32ZengOpen Medical PublishingHealth Psychology Research2420-81242022-06-01105Glossopharyngeal Neuralgia: Epidemiology, Risk factors, Pathophysiology, Differential diagnosis, and Treatment OptionsAndrew HanCarver MontgomeryAlexandra ZamoraEmilie WinderAdam D. KayeCaroline CarrollAlfonso AquinoJuyeon KakazuAlan D. Kaye# Purpose of Review This is a comprehensive review of the most recent literature on glossopharyngeal neuralgia (GPN), a relatively rare form of neuropathic facial pain. It covers the epidemiology, risk factors, pathophysiology, and differential diagnosis given that glossopharyngeal neuralgia can often be confused with other facial pain syndromes. Finally, we extensively review recent findings regarding medical or conservative measures, minimally invasive, and surgical options for potentially treating and managing glossopharyngeal neuralgia. # Recent Findings An in-depth analysis of the recent literature indicates that glossopharyngeal neuralgia is not only rare but its etiology and pathophysiology are complex and are often secondary to other disease processes. Regardless, current management options are shown to be effective in controlling pain. Conservatively, first-line management of GPN is carbamazepine, but gabapentin and eslicarbazepine acetate are suitable alternatives. In terms of current minimally invasive pain management techniques, pulsed radiofrequency ablation, nerve blocks, or percutaneous radiofrequency thermocoagulation are effective. Finally, surgical management involves microvascular decompression and rhizotomy. # Summary While there are currently many viable options for addressing glossopharyngeal neuralgia pain ranging from conservative to surgical management, the complex nature of GPN etiology, pathophysiology, and involved anatomical structures prompts further research for more effective ways to treat the disease.https://doi.org/10.52965/001c.36042 |
| spellingShingle | Andrew Han Carver Montgomery Alexandra Zamora Emilie Winder Adam D. Kaye Caroline Carroll Alfonso Aquino Juyeon Kakazu Alan D. Kaye Glossopharyngeal Neuralgia: Epidemiology, Risk factors, Pathophysiology, Differential diagnosis, and Treatment Options Health Psychology Research |
| title | Glossopharyngeal Neuralgia: Epidemiology, Risk factors, Pathophysiology, Differential diagnosis, and Treatment Options |
| title_full | Glossopharyngeal Neuralgia: Epidemiology, Risk factors, Pathophysiology, Differential diagnosis, and Treatment Options |
| title_fullStr | Glossopharyngeal Neuralgia: Epidemiology, Risk factors, Pathophysiology, Differential diagnosis, and Treatment Options |
| title_full_unstemmed | Glossopharyngeal Neuralgia: Epidemiology, Risk factors, Pathophysiology, Differential diagnosis, and Treatment Options |
| title_short | Glossopharyngeal Neuralgia: Epidemiology, Risk factors, Pathophysiology, Differential diagnosis, and Treatment Options |
| title_sort | glossopharyngeal neuralgia epidemiology risk factors pathophysiology differential diagnosis and treatment options |
| url | https://doi.org/10.52965/001c.36042 |
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