Lipidomic signatures linked to gut microbiota alterations in children and adolescents with type 2 diabetes mellitus and metabolic syndrome

Lipidomic signatures linked to gut microbiota alterations in children and adolescents with type 2 diabetes mellitus and metabolic syndrome

Abstract Youth-onset type 2 diabetes mellitus (T2DM) has an aggressive clinical course and is usually preceded by obesity and metabolic syndrome (MetS). Lipids have emerged as potential biomarkers for studying metabolic risk factors and predicting disease progression. An untargeted lipidomic analysi...

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Bibliographic Details
Main Authors: Shirley Mora-Godínez, Ana Laura de la Garza, Oscar Tamez-Rivera, Carolina Senés-Guerrero, Ana Karen Carrizales-Sánchez, Gerardo García-Rivas, Carmen Hernández-Brenes
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Children
Type 2 diabetes mellitus
Metabolic syndrome
Lipidomics
Gut microbiota
Online Access:https://doi.org/10.1038/s41598-025-04343-3
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