Osteopenia in Newborns with Spinal Canal Defects
Purpose: Fracture development is one of the complications in patients with spina bifida, with an incidence ranging from 11% to 30%. This study aimed to investigate the frequency of fractures, osteopenia, and the factors associated with these conditions in neonates with spina bifida followed at our h...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kirsehir Ahi Evran University
2024-12-01
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| Series: | Ahi Evran Medical Journal |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/3553654 |
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| Summary: | Purpose: Fracture development is one of the complications in patients with spina bifida, with an incidence ranging from 11% to 30%. This study aimed to investigate the frequency of fractures, osteopenia, and the factors associated with these conditions in neonates with spina bifida followed at our hospital.
Materials and Methods: Cases who were hospitalized and operated on in our neonatal intensive care unit with the diagnosis of meningomyelocele (MMS) between 01 December 2020 and 31 January 2023 constituted the study group and were evaluated retrospectively. Perinatal findings (gender, mode of delivery, gestational week, birth weight), operation time, postoperative sepsis, additional accompanying anomalies, length of stay, serum free thyroxine (fT4) and thyroid stimulating hormone (TSH) levels were examined and recorded from the patient files.
Results: A total of 89 neonates with MMS and encephalocele were evaluated. The median birth weight was 3000 g (range: 1800-4300 g), and the median gestational age was 38 weeks (range: 32-40 weeks). Hypocalcemia was present in 14 (15.7%) patients. One patient had a phosphorus level below 4 mg/dl. All infants had normal alkaline phosphatase levels. Fractures were observed in 5 (5.6%) patients, all of whom had paralysis in the lower extremities.
Conclusion: There are many risk factors for fracture development in children with spina bifida, and fractures can often be overlooked due to low ambulation capacity and sensory deficits. Close monitoring of bone quality and fracture development in these infants, along with medical treatment support when necessary, is recommended. |
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| ISSN: | 2619-9203 |