Epigenetic regulation of nuclear receptors: Implications for endocrine-related diseases and therapeutic strategies

Epigenetic regulation of nuclear receptors: Implications for endocrine-related diseases and therapeutic strategies

The expression and function of the receptor are controlled by epigenetic changes, such as DNA methylation, histone modification, and noncoding RNAs. These modifications play a pivotal role in receptor activity and can lead to or exacerbate endocrine-related diseases. This review examines the epigene...

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Bibliographic Details
Main Authors: Yixin Song, Kexin Zhang, Jingwen Zhang, Qinying Li, Na Huang, Yujie Ma, Ningning Hou, Fang Han, Chengxia Kan, Xiaodong Sun
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-07-01
Series:Genes and Diseases
Subjects:
Androgen receptor
Breast cancer
DNA methylation
Epigenetic modulation
Estrogen receptor
Histone modification
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304224002782
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