Aminophosphinates against Helicobacter pylori ureolysis-Biochemical and whole-cell inhibition characteristics.

Urease is an important virulence factor from Helicobacter pylori that enables bacterial colonization of human gastric mucosa. Specific inhibition of urease activity can be regarded as a promising adjuvant strategy for eradication of this pathogen. A group of organophosphorus inhibitors of urease, na...

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Main Authors: Katarzyna Macegoniuk, Ewa Grela, Monika Biernat, Mateusz Psurski, Grażyna Gościniak, Anna Dziełak, Artur Mucha, Joanna Wietrzyk, Łukasz Berlicki, Agnieszka Grabowiecka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0182437&type=printable
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