Acute aortic occlusion associated with COVID‐19: A rare complication of a not so rare disease

Abstract Recent literature has reported a high prevalence of thrombotic events associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) responsible for causing coronavirus disease 2019 (COVID‐19) infection. Although venous thromboembolism complications have been well studied, art...

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Main Authors: Ryan Lee, Robert Hsu
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Journal of the American College of Emergency Physicians Open
Subjects:
Online Access:https://doi.org/10.1002/emp2.12730
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author Ryan Lee
Robert Hsu
author_facet Ryan Lee
Robert Hsu
author_sort Ryan Lee
collection DOAJ
description Abstract Recent literature has reported a high prevalence of thrombotic events associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) responsible for causing coronavirus disease 2019 (COVID‐19) infection. Although venous thromboembolism complications have been well studied, arterial thrombosis is less well described. Our aim is to describe acute aortoiliac occlusion (AAO), itself a rare condition, as a complication of COVID‐19 infection and review existing literature regarding its presentation and available treatment modalities. Over a 2‐week span in late 2021, 2 patients with recent COVID‐19 infection presented to our tertiary care hospital with AAO. Each case was treated with a multimodal therapeutic approach, including vascular interventional radiology guided thrombolysis, vascular surgical approach, and systemic anticoagulation. Although two separate primary approaches were taken, each resulted in high morbidity and death in both cases. Acute aortic occlusion is a rare disease associated with high morbidity and mortality. COVID‐19 has further been associated with arterial thromboembolic complications, including AAO, as presented here. More research is needed to identify patients at highest risk of developing arterial thromboembolic disease after COVID‐19 infection as well as to determine ideal therapeutic options in order to improve the exceedingly high morbidity and mortality associated with this complication.
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spelling doaj-art-5b6c7cd557bd40c5985fcf3398b24c9e2025-08-20T01:57:32ZengElsevierJournal of the American College of Emergency Physicians Open2688-11522022-06-0133n/an/a10.1002/emp2.12730Acute aortic occlusion associated with COVID‐19: A rare complication of a not so rare diseaseRyan Lee0Robert Hsu1Department of Emergency Medicine ChristianaCare Newark Delaware USADepartment of Emergency Medicine ChristianaCare Newark Delaware USAAbstract Recent literature has reported a high prevalence of thrombotic events associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) responsible for causing coronavirus disease 2019 (COVID‐19) infection. Although venous thromboembolism complications have been well studied, arterial thrombosis is less well described. Our aim is to describe acute aortoiliac occlusion (AAO), itself a rare condition, as a complication of COVID‐19 infection and review existing literature regarding its presentation and available treatment modalities. Over a 2‐week span in late 2021, 2 patients with recent COVID‐19 infection presented to our tertiary care hospital with AAO. Each case was treated with a multimodal therapeutic approach, including vascular interventional radiology guided thrombolysis, vascular surgical approach, and systemic anticoagulation. Although two separate primary approaches were taken, each resulted in high morbidity and death in both cases. Acute aortic occlusion is a rare disease associated with high morbidity and mortality. COVID‐19 has further been associated with arterial thromboembolic complications, including AAO, as presented here. More research is needed to identify patients at highest risk of developing arterial thromboembolic disease after COVID‐19 infection as well as to determine ideal therapeutic options in order to improve the exceedingly high morbidity and mortality associated with this complication.https://doi.org/10.1002/emp2.12730acute aortic occlusionanticoagulationCOVID‐19hypercoagulablethromboembolism
spellingShingle Ryan Lee
Robert Hsu
Acute aortic occlusion associated with COVID‐19: A rare complication of a not so rare disease
Journal of the American College of Emergency Physicians Open
acute aortic occlusion
anticoagulation
COVID‐19
hypercoagulable
thromboembolism
title Acute aortic occlusion associated with COVID‐19: A rare complication of a not so rare disease
title_full Acute aortic occlusion associated with COVID‐19: A rare complication of a not so rare disease
title_fullStr Acute aortic occlusion associated with COVID‐19: A rare complication of a not so rare disease
title_full_unstemmed Acute aortic occlusion associated with COVID‐19: A rare complication of a not so rare disease
title_short Acute aortic occlusion associated with COVID‐19: A rare complication of a not so rare disease
title_sort acute aortic occlusion associated with covid 19 a rare complication of a not so rare disease
topic acute aortic occlusion
anticoagulation
COVID‐19
hypercoagulable
thromboembolism
url https://doi.org/10.1002/emp2.12730
work_keys_str_mv AT ryanlee acuteaorticocclusionassociatedwithcovid19ararecomplicationofanotsoraredisease
AT roberthsu acuteaorticocclusionassociatedwithcovid19ararecomplicationofanotsoraredisease