Recent progress in multifunctional theranostic inorganic nanomaterials for cancer diagnostic imaging and therapy
The clinical management of cancer encompasses a wide array of conventional treatment options and numerous FDA-approved drugs; nevertheless, cancer continues to be one of the major reasons of death, mainly due to delayed diagnosis and restricted therapeutic efficacy. Recent advancements in nanotechno...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Next Nanotechnology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949829525000816 |
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| author | Namratha Parthasarathy Laxmanan Karthikeyan Mary Fabiola Raju Vivek |
| author_facet | Namratha Parthasarathy Laxmanan Karthikeyan Mary Fabiola Raju Vivek |
| author_sort | Namratha Parthasarathy |
| collection | DOAJ |
| description | The clinical management of cancer encompasses a wide array of conventional treatment options and numerous FDA-approved drugs; nevertheless, cancer continues to be one of the major reasons of death, mainly due to delayed diagnosis and restricted therapeutic efficacy. Recent advancements in nanotechnology have significantly enhanced the quality of the patient’s life, mainly through advanced diagnostic techniques and by developments in the field of nanomedicine for targeted drug delivery. This review explores the potential of inorganic multifunctional nanoparticles-(IMNPs) such as gold nanoparticles (Au NPs), quantum dots (QDs), mesoporous silica NPs (MSN NPs), copper NPs (Cu NPs), and magnetic (MNPs) in cancer theranostics nanomedicines. Furthermore, the recent progress in the utilization of these IMNPs for imaging and therapy of multidrug resistant cancers have been highlighted, illustrating their ability to facilitate real-time molecular tracking and enhance the therapeutic potential. The insights discussed in this review contribute to the strategic design of next-generation nanocarriers to address the limitations in cancer management and advancing clinical translation. |
| format | Article |
| id | doaj-art-5b5dd7c10b3c48dd8be8138bd62f2c12 |
| institution | DOAJ |
| issn | 2949-8295 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Next Nanotechnology |
| spelling | doaj-art-5b5dd7c10b3c48dd8be8138bd62f2c122025-08-20T03:15:39ZengElsevierNext Nanotechnology2949-82952025-01-01810021210.1016/j.nxnano.2025.100212Recent progress in multifunctional theranostic inorganic nanomaterials for cancer diagnostic imaging and therapyNamratha Parthasarathy0Laxmanan Karthikeyan1Mary Fabiola2Raju Vivek3Bio-Nano Theranostics Research Laboratory, Cancer Research Program (CRP), School of Life Sciences, Bharathiar University, Coimbatore, Tamil Nadu 641 046, India; PG and Research Department of Zoology, Nirmala College for Women, Redfields, Coimbatore, Tamil Nadu 641 018, IndiaIndustry-University Cooperation Foundation, Pukyong National University, Busan 48513, Republic of KoreaPG and Research Department of Zoology, Nirmala College for Women, Redfields, Coimbatore, Tamil Nadu 641 018, India; Corresponding authors.Bio-Nano Theranostics Research Laboratory, Cancer Research Program (CRP), School of Life Sciences, Bharathiar University, Coimbatore, Tamil Nadu 641 046, India; Corresponding authors.The clinical management of cancer encompasses a wide array of conventional treatment options and numerous FDA-approved drugs; nevertheless, cancer continues to be one of the major reasons of death, mainly due to delayed diagnosis and restricted therapeutic efficacy. Recent advancements in nanotechnology have significantly enhanced the quality of the patient’s life, mainly through advanced diagnostic techniques and by developments in the field of nanomedicine for targeted drug delivery. This review explores the potential of inorganic multifunctional nanoparticles-(IMNPs) such as gold nanoparticles (Au NPs), quantum dots (QDs), mesoporous silica NPs (MSN NPs), copper NPs (Cu NPs), and magnetic (MNPs) in cancer theranostics nanomedicines. Furthermore, the recent progress in the utilization of these IMNPs for imaging and therapy of multidrug resistant cancers have been highlighted, illustrating their ability to facilitate real-time molecular tracking and enhance the therapeutic potential. The insights discussed in this review contribute to the strategic design of next-generation nanocarriers to address the limitations in cancer management and advancing clinical translation.http://www.sciencedirect.com/science/article/pii/S2949829525000816Inorganic nanoparticlesCancer theranosticsImagingTherapyCancer |
| spellingShingle | Namratha Parthasarathy Laxmanan Karthikeyan Mary Fabiola Raju Vivek Recent progress in multifunctional theranostic inorganic nanomaterials for cancer diagnostic imaging and therapy Next Nanotechnology Inorganic nanoparticles Cancer theranostics Imaging Therapy Cancer |
| title | Recent progress in multifunctional theranostic inorganic nanomaterials for cancer diagnostic imaging and therapy |
| title_full | Recent progress in multifunctional theranostic inorganic nanomaterials for cancer diagnostic imaging and therapy |
| title_fullStr | Recent progress in multifunctional theranostic inorganic nanomaterials for cancer diagnostic imaging and therapy |
| title_full_unstemmed | Recent progress in multifunctional theranostic inorganic nanomaterials for cancer diagnostic imaging and therapy |
| title_short | Recent progress in multifunctional theranostic inorganic nanomaterials for cancer diagnostic imaging and therapy |
| title_sort | recent progress in multifunctional theranostic inorganic nanomaterials for cancer diagnostic imaging and therapy |
| topic | Inorganic nanoparticles Cancer theranostics Imaging Therapy Cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2949829525000816 |
| work_keys_str_mv | AT namrathaparthasarathy recentprogressinmultifunctionaltheranosticinorganicnanomaterialsforcancerdiagnosticimagingandtherapy AT laxmanankarthikeyan recentprogressinmultifunctionaltheranosticinorganicnanomaterialsforcancerdiagnosticimagingandtherapy AT maryfabiola recentprogressinmultifunctionaltheranosticinorganicnanomaterialsforcancerdiagnosticimagingandtherapy AT rajuvivek recentprogressinmultifunctionaltheranosticinorganicnanomaterialsforcancerdiagnosticimagingandtherapy |