Yttrium-90 selective internal radiation therapy on liver cancer: the past, the present, and the future

Yttrium-90 selective internal radiation therapy (90Y-SIRT) is a treatment technique that delivers radioactive microspheres precisely to the arterial vascular bed of neoplasms, utilizing beta radiation to administer a high local dose of radiation to the neoplasm tissues. This technology has demonstra...

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Main Authors: Jingqin MA, Linhong ZHANG, Minjie YANG, Jiabin CAI, Ying FANG, Rong LIU, Xudong QU, Lingxiao LIU, Zhiping YAN
Format: Article
Language:English
Published: Shanghai Chinese Clinical Medicine Press Co., Ltd. 2025-02-01
Series:Zhongguo Linchuang Yixue
Subjects:
Online Access:https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20250142
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author Jingqin MA
Linhong ZHANG
Minjie YANG
Jiabin CAI
Ying FANG
Rong LIU
Xudong QU
Lingxiao LIU
Zhiping YAN
author_facet Jingqin MA
Linhong ZHANG
Minjie YANG
Jiabin CAI
Ying FANG
Rong LIU
Xudong QU
Lingxiao LIU
Zhiping YAN
author_sort Jingqin MA
collection DOAJ
description Yttrium-90 selective internal radiation therapy (90Y-SIRT) is a treatment technique that delivers radioactive microspheres precisely to the arterial vascular bed of neoplasms, utilizing beta radiation to administer a high local dose of radiation to the neoplasm tissues. This technology has demonstrated significant efficacy in patients with unresectable pirmary liver cancers and liver metastases. This article systematically reviews the development history and clinical application status of 90Y-SIRT in the treatment of liver cancer, and looks forward to future development directions.
format Article
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institution OA Journals
issn 1008-6358
language English
publishDate 2025-02-01
publisher Shanghai Chinese Clinical Medicine Press Co., Ltd.
record_format Article
series Zhongguo Linchuang Yixue
spelling doaj-art-5b5bc42ca64949e2b7463ebe81d163332025-08-20T02:00:59ZengShanghai Chinese Clinical Medicine Press Co., Ltd.Zhongguo Linchuang Yixue1008-63582025-02-013213810.12025/j.issn.1008-6358.2025.2025014220250142Yttrium-90 selective internal radiation therapy on liver cancer: the past, the present, and the futureJingqin MA0Linhong ZHANG1Minjie YANG2Jiabin CAI3Ying FANG4Rong LIU5Xudong QU6Lingxiao LIU7Zhiping YAN8Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaYttrium-90 selective internal radiation therapy (90Y-SIRT) is a treatment technique that delivers radioactive microspheres precisely to the arterial vascular bed of neoplasms, utilizing beta radiation to administer a high local dose of radiation to the neoplasm tissues. This technology has demonstrated significant efficacy in patients with unresectable pirmary liver cancers and liver metastases. This article systematically reviews the development history and clinical application status of 90Y-SIRT in the treatment of liver cancer, and looks forward to future development directions.https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20250142yttrium-90selective internal radiation therapyliver cancer
spellingShingle Jingqin MA
Linhong ZHANG
Minjie YANG
Jiabin CAI
Ying FANG
Rong LIU
Xudong QU
Lingxiao LIU
Zhiping YAN
Yttrium-90 selective internal radiation therapy on liver cancer: the past, the present, and the future
Zhongguo Linchuang Yixue
yttrium-90
selective internal radiation therapy
liver cancer
title Yttrium-90 selective internal radiation therapy on liver cancer: the past, the present, and the future
title_full Yttrium-90 selective internal radiation therapy on liver cancer: the past, the present, and the future
title_fullStr Yttrium-90 selective internal radiation therapy on liver cancer: the past, the present, and the future
title_full_unstemmed Yttrium-90 selective internal radiation therapy on liver cancer: the past, the present, and the future
title_short Yttrium-90 selective internal radiation therapy on liver cancer: the past, the present, and the future
title_sort yttrium 90 selective internal radiation therapy on liver cancer the past the present and the future
topic yttrium-90
selective internal radiation therapy
liver cancer
url https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20250142
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