When public health emergencies hit the front line: a qualitative study of the patient experience in the emergency department and outpatient infectious disease clinic during the 2022 Mpox clade IIb outbreak

Abstract Background The World Health Organization (WHO) declared mpox clade IIb a Public Health Emergency of International Concern (PHEIC) in July 2022. During the clade IIb epidemic, patients presented to both Emergency Departments (ED) and Infectious Disease (ID) clinics for care. Given the uncert...

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Main Authors: Molly Brick, David Rudolph, Gaby Dashler, Amanda Varnauskas, Luxi Qiao, Matthew M. Hamill, Joyce L. Jones, William Garneau, Mustapha Saheed, Gabor Kelen, Kelly Gebo, Bhakti Hansoti
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Infectious Diseases
Online Access:https://doi.org/10.1186/s12879-025-11124-w
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author Molly Brick
David Rudolph
Gaby Dashler
Amanda Varnauskas
Luxi Qiao
Matthew M. Hamill
Joyce L. Jones
William Garneau
Mustapha Saheed
Gabor Kelen
Kelly Gebo
Bhakti Hansoti
author_facet Molly Brick
David Rudolph
Gaby Dashler
Amanda Varnauskas
Luxi Qiao
Matthew M. Hamill
Joyce L. Jones
William Garneau
Mustapha Saheed
Gabor Kelen
Kelly Gebo
Bhakti Hansoti
author_sort Molly Brick
collection DOAJ
description Abstract Background The World Health Organization (WHO) declared mpox clade IIb a Public Health Emergency of International Concern (PHEIC) in July 2022. During the clade IIb epidemic, patients presented to both Emergency Departments (ED) and Infectious Disease (ID) clinics for care. Given the uncertainty and limited knowledge of mpox in 2022, we sought to understand the patient experience to inform service delivery for future outbreaks. Methods A retrospective qualitative study enrolled patients who presented to five EDs and one ID clinic in the Johns Hopkins Health System who tested positive for mpox virus (MPXV) between June 1 and December 31, 2022. Patient interviews were conducted in pairs with one researcher as the interviewer and a second as note-taker. A semi-structured interview guide with post-interview coding for content analysis was used to ascertain clinical factors, individual factors, and system factors that impacted the patient experience. Results Of 73 patients who tested positive for MPXV, 47 (64.4%) presented to EDs and 26 (35.6%) to the ID clinic; 23 (31.5%) agreed to participate [n = 13 ED, 27.7%; n = 10 ID, 38.5%]. All identified as male, median age was 36 years [IQR 31–41], 65.2% Black [n = 7 ED, 53.8%; n = 7 ID, 70.0%], 87.0% men who have sex with men [n = 10 ED, 76.9%; n = 10 ID, 100%], 69.6% were people living with HIV [n = 7 ED, 53.8%; n = 9 ID, 90.0%]. Participants diagnosed in EDs perceived difficulties with follow up and isolation, desired more information about tecoviromat, and nearly half reported no contact from local health departments for follow up care or tecoviromat access. Participants presenting to the ID clinic endorsed positive experiences tied to an established and trusted medical home. Stigma, loneliness, and mental health difficulties were consistent themes for all participants. Conclusion Patients present to various venues for infectious diseases such as mpox. Many present to EDs as a safety net service or for more severe disease manifestations. Institutional partnerships between ED, ID, and public health authorities, ongoing training, an on-call system for infectious disease threats, de-stigmatization, and focus on successful linkage-to-care pathways are potential ways to improve responses for future novel infectious disease outbreaks.
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spelling doaj-art-5b57cedce8724098b5bc3efcf93dbb412025-08-20T02:00:12ZengBMCBMC Infectious Diseases1471-23342025-05-0125111110.1186/s12879-025-11124-wWhen public health emergencies hit the front line: a qualitative study of the patient experience in the emergency department and outpatient infectious disease clinic during the 2022 Mpox clade IIb outbreakMolly Brick0David Rudolph1Gaby Dashler2Amanda Varnauskas3Luxi Qiao4Matthew M. Hamill5Joyce L. Jones6William Garneau7Mustapha Saheed8Gabor Kelen9Kelly Gebo10Bhakti Hansoti11Johns Hopkins Department of Emergency MedicineJohns Hopkins Department of Emergency MedicineJohns Hopkins Department of Emergency MedicineJohns Hopkins Department of Emergency MedicineJohns Hopkins Department of Emergency MedicineJohns Hopkins Department of Medicine/Division of Infectious DiseasesJohns Hopkins Department of Medicine/Division of Infectious DiseasesJohns Hopkins Department of Medicine/Division of Hospital MedicineJohns Hopkins Department of Emergency MedicineJohns Hopkins Department of Emergency MedicineJohns Hopkins Department of Medicine/Division of Infectious DiseasesJohns Hopkins Department of Emergency MedicineAbstract Background The World Health Organization (WHO) declared mpox clade IIb a Public Health Emergency of International Concern (PHEIC) in July 2022. During the clade IIb epidemic, patients presented to both Emergency Departments (ED) and Infectious Disease (ID) clinics for care. Given the uncertainty and limited knowledge of mpox in 2022, we sought to understand the patient experience to inform service delivery for future outbreaks. Methods A retrospective qualitative study enrolled patients who presented to five EDs and one ID clinic in the Johns Hopkins Health System who tested positive for mpox virus (MPXV) between June 1 and December 31, 2022. Patient interviews were conducted in pairs with one researcher as the interviewer and a second as note-taker. A semi-structured interview guide with post-interview coding for content analysis was used to ascertain clinical factors, individual factors, and system factors that impacted the patient experience. Results Of 73 patients who tested positive for MPXV, 47 (64.4%) presented to EDs and 26 (35.6%) to the ID clinic; 23 (31.5%) agreed to participate [n = 13 ED, 27.7%; n = 10 ID, 38.5%]. All identified as male, median age was 36 years [IQR 31–41], 65.2% Black [n = 7 ED, 53.8%; n = 7 ID, 70.0%], 87.0% men who have sex with men [n = 10 ED, 76.9%; n = 10 ID, 100%], 69.6% were people living with HIV [n = 7 ED, 53.8%; n = 9 ID, 90.0%]. Participants diagnosed in EDs perceived difficulties with follow up and isolation, desired more information about tecoviromat, and nearly half reported no contact from local health departments for follow up care or tecoviromat access. Participants presenting to the ID clinic endorsed positive experiences tied to an established and trusted medical home. Stigma, loneliness, and mental health difficulties were consistent themes for all participants. Conclusion Patients present to various venues for infectious diseases such as mpox. Many present to EDs as a safety net service or for more severe disease manifestations. Institutional partnerships between ED, ID, and public health authorities, ongoing training, an on-call system for infectious disease threats, de-stigmatization, and focus on successful linkage-to-care pathways are potential ways to improve responses for future novel infectious disease outbreaks.https://doi.org/10.1186/s12879-025-11124-w
spellingShingle Molly Brick
David Rudolph
Gaby Dashler
Amanda Varnauskas
Luxi Qiao
Matthew M. Hamill
Joyce L. Jones
William Garneau
Mustapha Saheed
Gabor Kelen
Kelly Gebo
Bhakti Hansoti
When public health emergencies hit the front line: a qualitative study of the patient experience in the emergency department and outpatient infectious disease clinic during the 2022 Mpox clade IIb outbreak
BMC Infectious Diseases
title When public health emergencies hit the front line: a qualitative study of the patient experience in the emergency department and outpatient infectious disease clinic during the 2022 Mpox clade IIb outbreak
title_full When public health emergencies hit the front line: a qualitative study of the patient experience in the emergency department and outpatient infectious disease clinic during the 2022 Mpox clade IIb outbreak
title_fullStr When public health emergencies hit the front line: a qualitative study of the patient experience in the emergency department and outpatient infectious disease clinic during the 2022 Mpox clade IIb outbreak
title_full_unstemmed When public health emergencies hit the front line: a qualitative study of the patient experience in the emergency department and outpatient infectious disease clinic during the 2022 Mpox clade IIb outbreak
title_short When public health emergencies hit the front line: a qualitative study of the patient experience in the emergency department and outpatient infectious disease clinic during the 2022 Mpox clade IIb outbreak
title_sort when public health emergencies hit the front line a qualitative study of the patient experience in the emergency department and outpatient infectious disease clinic during the 2022 mpox clade iib outbreak
url https://doi.org/10.1186/s12879-025-11124-w
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