18F-FDG positron emission tomography in the diagnosis and staging of marginal zone non-Hodgkin lymphomas
Objective: to investigate the diagnostic value of 18F-FDG positron emission tomography (PET) in the diagnosis and staging of marginal zone non-Hodgkin lymphomas (NHLs).Objective: to investigate the diagnostic value of 18F-FDG positron emission tomography (PET) in the diagnosis and staging of margi...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Luchevaya Diagnostika, LLC
2016-02-01
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| Series: | Вестник рентгенологии и радиологии |
| Subjects: | |
| Online Access: | https://www.russianradiology.ru/jour/article/view/2 |
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| Summary: | Objective: to investigate the diagnostic value of 18F-FDG positron emission tomography (PET) in the diagnosis and staging of marginal zone non-Hodgkin lymphomas (NHLs).Objective: to investigate the diagnostic value of 18F-FDG positron emission tomography (PET) in the diagnosis and staging of marginal zone non-Hodgkin lymphomas (NHLs).Material and methods. Twenty-four patients with new-onset NHLs were examined. Extranodal MALT lymphoma, splenic marginal zone lymphoma (MZL), and nodal MZL lymphoma were diagnosed in 18, 3, and 3 patients, respectively. 18F-FDG PЕT was carried out by the standard protocol via whole-body examination, by estimating the standardized tracer uptake value (SUVmax) in the abnormal foci.Results. Most (83.3%) of the examinees were found to have abnormal tracer hyperfixation foci. The mean SUVmax was 5.05±0.9. There was no correlation between SUVmax in the tumor foci and their metabolic sizes (r = 0.1; p = 0.7). No significant differences between the mean SUVmax were found in patients with different histological types of MZL (p > 0.05). Disease staging by PET and other diagnostic methods yielded contradictory results in three patients. The final analysis suggested that the stage had been correctly determined in all the 3 patients from PET findings.Conclusion. The results of 18F-FDG PET suggest that it is of high diagnostic value in imaging marginal zone NHLs. The major advantage of PET is that it can accurately stage the disease, which can provide a rationale for optimal treatment policy. |
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| ISSN: | 0042-4676 2619-0478 |