Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X.

Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X.

The prevalence of obesity (body mass index (BMI) > or =30 kg/m(2)) is higher in African Americans than in European Americans, even after adjustment for socioeconomic factors, suggesting that genetic factors may explain some of the difference. To identify genetic loci influencing BMI, we carried o...

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Main Authors: Ching-Yu Cheng, W H Linda Kao, Nick Patterson, Arti Tandon, Christopher A Haiman, Tamara B Harris, Chao Xing, Esther M John, Christine B Ambrosone, Frederick L Brancati, Josef Coresh, Michael F Press, Rulan S Parekh, Michael J Klag, Lucy A Meoni, Wen-Chi Hsueh, Laura Fejerman, Ludmila Pawlikowska, Matthew L Freedman, Lina H Jandorf, Elisa V Bandera, Gregory L Ciupak, Michael A Nalls, Ermeg L Akylbekova, Eric S Orwoll, Tennille S Leak, Iva Miljkovic, Rongling Li, Giske Ursin, Leslie Bernstein, Kristin Ardlie, Herman A Taylor, Eric Boerwinckle, Joseph M Zmuda, Brian E Henderson, James G Wilson, David Reich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000490&type=printable
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