Cohort profile: the Funen Diabetes Database—a population-based cohort of patients with diabetes in Denmark

Purpose Detailed population-based data are essential to understanding the epidemiology of diabetes and its clinical course. This article describes the Funen Diabetes Database (FDDB). The purpose of the FDDB was to serve as a shared electronic medical record system for healthcare professionals treati...

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Main Authors: Reimar Wernich Thomsen, Henrik Toft Sørensen, Jan Erik Henriksen, Lars Pedersen, Kasper Adelborg, Péter Szentkúti, Jens Sundbøll, Ole Hother-Nielsen, Henning Beck-Nielsen
Format: Article
Language:English
Published: BMJ Publishing Group 2020-04-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/4/e035492.full
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author Reimar Wernich Thomsen
Henrik Toft Sørensen
Jan Erik Henriksen
Lars Pedersen
Kasper Adelborg
Péter Szentkúti
Jens Sundbøll
Ole Hother-Nielsen
Henning Beck-Nielsen
author_facet Reimar Wernich Thomsen
Henrik Toft Sørensen
Jan Erik Henriksen
Lars Pedersen
Kasper Adelborg
Péter Szentkúti
Jens Sundbøll
Ole Hother-Nielsen
Henning Beck-Nielsen
author_sort Reimar Wernich Thomsen
collection DOAJ
description Purpose Detailed population-based data are essential to understanding the epidemiology of diabetes and its clinical course. This article describes the Funen Diabetes Database (FDDB). The purpose of the FDDB was to serve as a shared electronic medical record system for healthcare professionals treating patients with diabetes. The cohort can also be used for research.Participants The FDDB covers a geographical area of almost 500 000 Danish inhabitants. It currently includes 3691 patients with type 1 diabetes, 19 085 patients with type 2 diabetes, 292 patients with other types of diabetes and 5992 patients with an unknown type of diabetes. Patients have been continuously enrolled from general practitioners and endocrinology departments in the Funen area in Denmark since 2003. Patients undergo a clinical work-up at their first diabetes contact and during follow-up visits. The information collected includes type of diabetes contact, blood pressure, height, weight, lifestyle factors (smoking, exercise), laboratory records (eg, haemoglobin A1c and cholesterol levels), results from foot examinations (eg, pulse, cutaneous sensitivity and ankle brachial index), results from eye examinations (eg, degree of retinopathy assessed by retinal photo and eye examination), glucose-lowering drugs and diabetic complications.Findings to date The FDDB cohort was followed for a total of 212 234 person-years up to 2016. A cross-sectional study described the prevalence of diabetic retinopathy and its associated risk factors. The clinical outcomes of patients with type 1 diabetes, type 2 diabetes and latent autoimmune diabetes in adults have been assessed. Linkage to population-based medical registries with complete follow-up has enabled the collection of extensive continuous data on general practice contacts, diagnoses and procedures from hospital contacts, medication use and mortality.Future plans The FDDB serves as a strong data resource that will be used in future studies of diabetes epidemiology with focus on occurrence, risk factors, treatment, complications and prognosis.
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spelling doaj-art-5b4a9e540a8a4fb5ba1aa18823d9bde22025-08-20T02:19:55ZengBMJ Publishing GroupBMJ Open2044-60552020-04-0110410.1136/bmjopen-2019-035492Cohort profile: the Funen Diabetes Database—a population-based cohort of patients with diabetes in DenmarkReimar Wernich Thomsen0Henrik Toft Sørensen1Jan Erik Henriksen2Lars Pedersen3Kasper Adelborg4Péter Szentkúti5Jens Sundbøll6Ole Hother-Nielsen7Henning Beck-Nielsen81 Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkSteno Diabetes Centre Odense, Odense University Hospital, Odense, DenmarkDepartment of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Allé 43-45, 8200, Aarhus, Denmark1 Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Epidemiology, Aarhus Universitetshospital, Aarhus, DenmarkDepartment of Clinical Epidemiology, Aarhus Universitetshospital, Aarhus, DenmarkSteno Diabetes Centre Odense, Odense University Hospital, Odense, DenmarkSteno Diabetes Centre Odense, Odense University Hospital, Odense, DenmarkPurpose Detailed population-based data are essential to understanding the epidemiology of diabetes and its clinical course. This article describes the Funen Diabetes Database (FDDB). The purpose of the FDDB was to serve as a shared electronic medical record system for healthcare professionals treating patients with diabetes. The cohort can also be used for research.Participants The FDDB covers a geographical area of almost 500 000 Danish inhabitants. It currently includes 3691 patients with type 1 diabetes, 19 085 patients with type 2 diabetes, 292 patients with other types of diabetes and 5992 patients with an unknown type of diabetes. Patients have been continuously enrolled from general practitioners and endocrinology departments in the Funen area in Denmark since 2003. Patients undergo a clinical work-up at their first diabetes contact and during follow-up visits. The information collected includes type of diabetes contact, blood pressure, height, weight, lifestyle factors (smoking, exercise), laboratory records (eg, haemoglobin A1c and cholesterol levels), results from foot examinations (eg, pulse, cutaneous sensitivity and ankle brachial index), results from eye examinations (eg, degree of retinopathy assessed by retinal photo and eye examination), glucose-lowering drugs and diabetic complications.Findings to date The FDDB cohort was followed for a total of 212 234 person-years up to 2016. A cross-sectional study described the prevalence of diabetic retinopathy and its associated risk factors. The clinical outcomes of patients with type 1 diabetes, type 2 diabetes and latent autoimmune diabetes in adults have been assessed. Linkage to population-based medical registries with complete follow-up has enabled the collection of extensive continuous data on general practice contacts, diagnoses and procedures from hospital contacts, medication use and mortality.Future plans The FDDB serves as a strong data resource that will be used in future studies of diabetes epidemiology with focus on occurrence, risk factors, treatment, complications and prognosis.https://bmjopen.bmj.com/content/10/4/e035492.full
spellingShingle Reimar Wernich Thomsen
Henrik Toft Sørensen
Jan Erik Henriksen
Lars Pedersen
Kasper Adelborg
Péter Szentkúti
Jens Sundbøll
Ole Hother-Nielsen
Henning Beck-Nielsen
Cohort profile: the Funen Diabetes Database—a population-based cohort of patients with diabetes in Denmark
BMJ Open
title Cohort profile: the Funen Diabetes Database—a population-based cohort of patients with diabetes in Denmark
title_full Cohort profile: the Funen Diabetes Database—a population-based cohort of patients with diabetes in Denmark
title_fullStr Cohort profile: the Funen Diabetes Database—a population-based cohort of patients with diabetes in Denmark
title_full_unstemmed Cohort profile: the Funen Diabetes Database—a population-based cohort of patients with diabetes in Denmark
title_short Cohort profile: the Funen Diabetes Database—a population-based cohort of patients with diabetes in Denmark
title_sort cohort profile the funen diabetes database a population based cohort of patients with diabetes in denmark
url https://bmjopen.bmj.com/content/10/4/e035492.full
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