The Design of a Randomized Controlled Active Comparator Strategy Trial for Gout: Treat to Target Serum Urate Versus Treat to Avoid Symptoms

The Design of a Randomized Controlled Active Comparator Strategy Trial for Gout: Treat to Target Serum Urate Versus Treat to Avoid Symptoms

Objective Controversy persists regarding the optimal management of gout in routine primary care. There is a lack of clarity on whether treating to a target serum urate (TTT‐SU) versus treating to avoid symptoms (TTASx) is more effective. Methods We designed a randomized controlled comparative effect...

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Main Authors: Daniel H. Solomon, Misti Paudel, Shravani Chitineni, Ana Fernandes, Tammy Pham, Shreya Billa, Chio Yokose, Kiara Tan, Julien J. Dedier, Maureen D. Dubreuil, John D. Fitzgerald, Sally L. Hodder, Tuhina Neogi, Michael H. Pillinger, Kevin R. Riggs, Kenneth G. Saag, Paul G. Shekelle, Zoe Tseng, Michael Toprover, David S. Wei, Michael J. Barry, Hyon K. Choi
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:ACR Open Rheumatology
Online Access:https://doi.org/10.1002/acr2.70012
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