Detection and staging of Alzheimer's disease by plasma pTau217 on a high throughput immunoassay platformResearch in context

Detection and staging of Alzheimer's disease by plasma pTau217 on a high throughput immunoassay platformResearch in context

Summary: Background: Plasma phospho-tau 217 (pTau217) assays can accurately detect Alzheimer's disease (AD) pathology, but clinical application is limited by the need for specialised equipment. This study tests the performance of a plasma pTau217 assay performed on the Lumipulse-G® platform, t...

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Bibliographic Details
Main Authors: Azadeh Feizpour, James David Doecke, Vincent Doré, Natasha Krishnadas, Kun Huang, Pierrick Bourgeat, Simon Matthew Laws, Christopher Fowler, Joanne Robertson, Lucy Mackintosh, Scott Ayton, Ralph Martins, Stephanie Ruth Rainey-Smith, Kevin Taddei, Larry Ward, Eddie Stage, Anthony Wilson Bannon, Colin Louis Masters, Jurgen Fripp, Victor Luis Villemagne, Christopher Cleon Rowe
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:EBioMedicine
Subjects:
Alzheimer's disease
Plasma biomarker
Phospho-tau
pTau217
Positron emission tomography
PET
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424004419
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