A novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular joint
Abstract This study aimed to evaluate the effectiveness of a new combined treatment approach using arthrocentesis, hyaluronic acid (HA) injection, mandibular manipulation (MM), and the Twin-Block appliance (TBA) for managing acute anterior disc displacement without reduction (ADDwoR). A retrospectiv...
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Nature Portfolio
2025-02-01
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| Online Access: | https://doi.org/10.1038/s41598-025-88622-z |
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| author | Zhi-qiang Song Chen‑xi Li Zhong‑cheng Gong |
| author_facet | Zhi-qiang Song Chen‑xi Li Zhong‑cheng Gong |
| author_sort | Zhi-qiang Song |
| collection | DOAJ |
| description | Abstract This study aimed to evaluate the effectiveness of a new combined treatment approach using arthrocentesis, hyaluronic acid (HA) injection, mandibular manipulation (MM), and the Twin-Block appliance (TBA) for managing acute anterior disc displacement without reduction (ADDwoR). A retrospective cross-sectional study was designed. Thirty-seven patients (38 joints) diagnosed with acute ADDwoR were treated with arthrocentesis plus HA combined with MM and TBA in turn from January 2022 to December 2023. The maximum mouth opening (MMO), visual analogue scale (VAS) pain score, condyle/disc position were measured and comparatively analyzed at baseline and one week, three and six months post-treatment. Analysis of variance, Dunnett’s T3 analysis, and paired samples t-tests were conducted for statistical analyses setting the threshold for statistical significance at P < 0.05. This treatment achieved a success rate of 94.59% (35/37). After one week of treatment, the MMO exhibited a statistically significant improvement, while the VAS pain scores showed a statistically significant decrease (P < 0.001). Magnetic resonance imaging revealed that at six months post-treatment, there was a significant forward shift in the condylar position compared with pre-treatment (P < 0.001),alongside a significant backward movement of the disc on the affected side (P < 0.001).The combination of arthrocentesis plus HA, MM, and TBA can effectively relieve clinical symptoms and restore the disc-condylar relationship in patients with acute ADDwoR. |
| format | Article |
| id | doaj-art-5b2a141f7fd24dd0b1fbe0e1beeb265c |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nature Portfolio |
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| spelling | doaj-art-5b2a141f7fd24dd0b1fbe0e1beeb265c2025-02-09T12:37:28ZengNature PortfolioScientific Reports2045-23222025-02-0115111210.1038/s41598-025-88622-zA novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular jointZhi-qiang Song0Chen‑xi Li1Zhong‑cheng Gong2Department of Oral and Maxillofacial Oncology & Surgery, School / Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical UniversityDepartment of Oral and Maxillofacial Oncology & Surgery, School / Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical UniversityDepartment of Oral and Maxillofacial Oncology & Surgery, School / Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical UniversityAbstract This study aimed to evaluate the effectiveness of a new combined treatment approach using arthrocentesis, hyaluronic acid (HA) injection, mandibular manipulation (MM), and the Twin-Block appliance (TBA) for managing acute anterior disc displacement without reduction (ADDwoR). A retrospective cross-sectional study was designed. Thirty-seven patients (38 joints) diagnosed with acute ADDwoR were treated with arthrocentesis plus HA combined with MM and TBA in turn from January 2022 to December 2023. The maximum mouth opening (MMO), visual analogue scale (VAS) pain score, condyle/disc position were measured and comparatively analyzed at baseline and one week, three and six months post-treatment. Analysis of variance, Dunnett’s T3 analysis, and paired samples t-tests were conducted for statistical analyses setting the threshold for statistical significance at P < 0.05. This treatment achieved a success rate of 94.59% (35/37). After one week of treatment, the MMO exhibited a statistically significant improvement, while the VAS pain scores showed a statistically significant decrease (P < 0.001). Magnetic resonance imaging revealed that at six months post-treatment, there was a significant forward shift in the condylar position compared with pre-treatment (P < 0.001),alongside a significant backward movement of the disc on the affected side (P < 0.001).The combination of arthrocentesis plus HA, MM, and TBA can effectively relieve clinical symptoms and restore the disc-condylar relationship in patients with acute ADDwoR.https://doi.org/10.1038/s41598-025-88622-zTemporomandibular jointAnterior disc displacement without reductionMandibular manipulationTwin-block |
| spellingShingle | Zhi-qiang Song Chen‑xi Li Zhong‑cheng Gong A novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular joint Scientific Reports Temporomandibular joint Anterior disc displacement without reduction Mandibular manipulation Twin-block |
| title | A novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular joint |
| title_full | A novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular joint |
| title_fullStr | A novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular joint |
| title_full_unstemmed | A novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular joint |
| title_short | A novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular joint |
| title_sort | novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular joint |
| topic | Temporomandibular joint Anterior disc displacement without reduction Mandibular manipulation Twin-block |
| url | https://doi.org/10.1038/s41598-025-88622-z |
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