Unilateral optic nerve aplasia associated with microphthalmos

Intraduction. Optic nerve aplasia is a rare developmental anomaly characterised by the congenital absence of the optic nerve, central retinal vessels and retinal ganglion cells that is seen most often in a unilaterally malformed eye. Case report. We reported a girl with a very rare anomaly of th...

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Main Authors: Stanković-Babić Gordana, Oros Ana, Cekić Sonja, Vujanović Milena, Babić Rade R.
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2012-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501203286S.pdf
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author Stanković-Babić Gordana
Oros Ana
Cekić Sonja
Vujanović Milena
Babić Rade R.
author_facet Stanković-Babić Gordana
Oros Ana
Cekić Sonja
Vujanović Milena
Babić Rade R.
author_sort Stanković-Babić Gordana
collection DOAJ
description Intraduction. Optic nerve aplasia is a rare developmental anomaly characterised by the congenital absence of the optic nerve, central retinal vessels and retinal ganglion cells that is seen most often in a unilaterally malformed eye. Case report. We reported a girl with a very rare anomaly of the eye, unilateral aplasia of the optic nerve and microphthalmia. We carried out a complete ophthalmological examination, A- and Bscan ultrasonography, magnetic resonance imaging (MRI) of the orbit and brain, pediatrician, neurological examinations and karyotype determination. The examined child was a third child from the third regular pregnancy, born at term (39 GS, BM 3100 g). Family ocular history was negative. The right corneal diameter was 7.5 mm and left 10 mm. On dilated fundus examination, the right eye showed the absence of optic nerve and central retinal vessels. B-scan echography showed a small right globe (axial length 13.80 mm), normal size left globe (axial length 18.30 mm) and the absence of optic nerve on the right eye. Physical and neurological findings and karyotype was normal. MRI of the orbits and brain marked asymmetry of globe size and unilateral absence of the optic nerve. The patient is under the control of a competent ophthalmologist and prosthetic. Conclusion. Further aesthetic and functional development of a young person is the primary goal in tracking this rare congenital optic nerve anomalies in the malformed eye.
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spelling doaj-art-5b2956e6b70e4b4881dba8876401bdc62025-08-20T01:57:25ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502012-01-0169328629010.2298/VSP1203286SUnilateral optic nerve aplasia associated with microphthalmosStanković-Babić GordanaOros AnaCekić SonjaVujanović MilenaBabić Rade R.Intraduction. Optic nerve aplasia is a rare developmental anomaly characterised by the congenital absence of the optic nerve, central retinal vessels and retinal ganglion cells that is seen most often in a unilaterally malformed eye. Case report. We reported a girl with a very rare anomaly of the eye, unilateral aplasia of the optic nerve and microphthalmia. We carried out a complete ophthalmological examination, A- and Bscan ultrasonography, magnetic resonance imaging (MRI) of the orbit and brain, pediatrician, neurological examinations and karyotype determination. The examined child was a third child from the third regular pregnancy, born at term (39 GS, BM 3100 g). Family ocular history was negative. The right corneal diameter was 7.5 mm and left 10 mm. On dilated fundus examination, the right eye showed the absence of optic nerve and central retinal vessels. B-scan echography showed a small right globe (axial length 13.80 mm), normal size left globe (axial length 18.30 mm) and the absence of optic nerve on the right eye. Physical and neurological findings and karyotype was normal. MRI of the orbits and brain marked asymmetry of globe size and unilateral absence of the optic nerve. The patient is under the control of a competent ophthalmologist and prosthetic. Conclusion. Further aesthetic and functional development of a young person is the primary goal in tracking this rare congenital optic nerve anomalies in the malformed eye.http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501203286S.pdfoptic nervecongenital abnormalitiesmicrophthalmosdiagnostic techniques and procedurestherapeutics
spellingShingle Stanković-Babić Gordana
Oros Ana
Cekić Sonja
Vujanović Milena
Babić Rade R.
Unilateral optic nerve aplasia associated with microphthalmos
Vojnosanitetski Pregled
optic nerve
congenital abnormalities
microphthalmos
diagnostic techniques and procedures
therapeutics
title Unilateral optic nerve aplasia associated with microphthalmos
title_full Unilateral optic nerve aplasia associated with microphthalmos
title_fullStr Unilateral optic nerve aplasia associated with microphthalmos
title_full_unstemmed Unilateral optic nerve aplasia associated with microphthalmos
title_short Unilateral optic nerve aplasia associated with microphthalmos
title_sort unilateral optic nerve aplasia associated with microphthalmos
topic optic nerve
congenital abnormalities
microphthalmos
diagnostic techniques and procedures
therapeutics
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501203286S.pdf
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AT orosana unilateralopticnerveaplasiaassociatedwithmicrophthalmos
AT cekicsonja unilateralopticnerveaplasiaassociatedwithmicrophthalmos
AT vujanovicmilena unilateralopticnerveaplasiaassociatedwithmicrophthalmos
AT babicrader unilateralopticnerveaplasiaassociatedwithmicrophthalmos