Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using Drosophila S2 Cells

Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using Drosophila S2 Cells

ABSTRACT Marburg marburgvirus (MARV) is a highly virulent human pathogen with limited therapeutic options. Recombinant MARV glycoprotein (GP) produced in Drosophila Schneider 2 (S2) cells has been extensively investigated as potential vaccine antigen with promising efficacy demonstrated in nonhuman...

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Bibliographic Details
Main Authors: Sven Göbel, Ludwig Mayerlen, Isabelle Yazel Eiser, Lisa Fichtmueller, David Clements, Udo Reichl, Yvonne Genzel, AxelT. Lehrer
Format: Article
Language:English
Published: Wiley-VCH 2025-05-01
Series:Engineering in Life Sciences
Subjects:
cell culture
Drosophila S2
Marburg virus
process intensification
vaccine
Online Access:https://doi.org/10.1002/elsc.70022
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