Weight Change and Its Association with Cardiometabolic Risk Markers in Overweight and Obese Women
Introduction. The effect of weight loss magnitude on cardiometabolic risk markers has been sparsely studied, particularly among overweight and obese women from low socioeconomic areas. Objectives. To examine the association of weight loss magnitude with changes in cardiometabolic risk markers in ove...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Obesity |
| Online Access: | http://dx.doi.org/10.1155/2020/3198326 |
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| author | Liyana Ahmad Zamri Geeta Appannah Siti Yazmin Zahari Sham Fazliana Mansor Rashidah Ambak Noor Safiza Mohd Nor Tahir Aris |
| author_facet | Liyana Ahmad Zamri Geeta Appannah Siti Yazmin Zahari Sham Fazliana Mansor Rashidah Ambak Noor Safiza Mohd Nor Tahir Aris |
| author_sort | Liyana Ahmad Zamri |
| collection | DOAJ |
| description | Introduction. The effect of weight loss magnitude on cardiometabolic risk markers has been sparsely studied, particularly among overweight and obese women from low socioeconomic areas. Objectives. To examine the association of weight loss magnitude with changes in cardiometabolic risk markers in overweight and obese women from low socioeconomic areas engaged in a lifestyle intervention. Methods. Analyses were performed on 243 women (mean body mass index 31.27 ± 4.14 kg/m2) who completed a 12-month lifestyle intervention in low socioeconomic communities in Klang Valley, Malaysia. Analysis of covariance (ANCOVA) was used to compare changes of cardiometabolic risk factors across weight change categories (2% gain, ±2% maintain, >2 to <5% loss, and 5 to 20% loss) within intervention and control group. Results. A graded association for changes in waist circumference, fasting insulin, and total cholesterol (p=0.002, for all variables) across the weight change categories were observed within the intervention group at six months postintervention. Participants who lost 5 to 20% of weight had the greatest improvements in those risk markers (−5.67 cm CI: −7.98 to −3.36, −4.27 μU/mL CI: −7.35, −1.19, and −0.59 mmol/L CI: −.99, −0.19, respectively) compared to those who did not. Those who lost >2% to <5% weight reduced more waist circumference (−4.24 cm CI: −5.44 to −3.04) and fasting insulin (−0.36 μU/mL CI: −1.95 to 1.24) than those who maintained or gained weight. No significant association was detected in changes of risk markers across the weight change categories within the control group except for waist circumference and adiponectin. Conclusion. Weight loss of >2 to <5% obtained through lifestyle intervention may represent a reasonable initial weight loss target for women in the low socioeconomic community as it led to improvements in selected risk markers, particularly of diabetes risk. |
| format | Article |
| id | doaj-art-5b26579c40324cf0a280f403c24e6281 |
| institution | OA Journals |
| issn | 2090-0708 2090-0716 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Obesity |
| spelling | doaj-art-5b26579c40324cf0a280f403c24e62812025-08-20T02:05:14ZengWileyJournal of Obesity2090-07082090-07162020-01-01202010.1155/2020/31983263198326Weight Change and Its Association with Cardiometabolic Risk Markers in Overweight and Obese WomenLiyana Ahmad Zamri0Geeta Appannah1Siti Yazmin Zahari Sham2Fazliana Mansor3Rashidah Ambak4Noor Safiza Mohd Nor5Tahir Aris6Endocrine and Metabolic Unit, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, 40170 Shah Alam, Selangor, MalaysiaDepartment of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, MalaysiaDepartment of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, MalaysiaEndocrine and Metabolic Unit, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, 40170 Shah Alam, Selangor, MalaysiaInstitute for Public Health, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, 40170 Shah Alam, Selangor, MalaysiaAllied Health Sciences Division, Ministry of Health Malaysia, 62050 Putrajaya, MalaysiaInstitute for Public Health, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, 40170 Shah Alam, Selangor, MalaysiaIntroduction. The effect of weight loss magnitude on cardiometabolic risk markers has been sparsely studied, particularly among overweight and obese women from low socioeconomic areas. Objectives. To examine the association of weight loss magnitude with changes in cardiometabolic risk markers in overweight and obese women from low socioeconomic areas engaged in a lifestyle intervention. Methods. Analyses were performed on 243 women (mean body mass index 31.27 ± 4.14 kg/m2) who completed a 12-month lifestyle intervention in low socioeconomic communities in Klang Valley, Malaysia. Analysis of covariance (ANCOVA) was used to compare changes of cardiometabolic risk factors across weight change categories (2% gain, ±2% maintain, >2 to <5% loss, and 5 to 20% loss) within intervention and control group. Results. A graded association for changes in waist circumference, fasting insulin, and total cholesterol (p=0.002, for all variables) across the weight change categories were observed within the intervention group at six months postintervention. Participants who lost 5 to 20% of weight had the greatest improvements in those risk markers (−5.67 cm CI: −7.98 to −3.36, −4.27 μU/mL CI: −7.35, −1.19, and −0.59 mmol/L CI: −.99, −0.19, respectively) compared to those who did not. Those who lost >2% to <5% weight reduced more waist circumference (−4.24 cm CI: −5.44 to −3.04) and fasting insulin (−0.36 μU/mL CI: −1.95 to 1.24) than those who maintained or gained weight. No significant association was detected in changes of risk markers across the weight change categories within the control group except for waist circumference and adiponectin. Conclusion. Weight loss of >2 to <5% obtained through lifestyle intervention may represent a reasonable initial weight loss target for women in the low socioeconomic community as it led to improvements in selected risk markers, particularly of diabetes risk.http://dx.doi.org/10.1155/2020/3198326 |
| spellingShingle | Liyana Ahmad Zamri Geeta Appannah Siti Yazmin Zahari Sham Fazliana Mansor Rashidah Ambak Noor Safiza Mohd Nor Tahir Aris Weight Change and Its Association with Cardiometabolic Risk Markers in Overweight and Obese Women Journal of Obesity |
| title | Weight Change and Its Association with Cardiometabolic Risk Markers in Overweight and Obese Women |
| title_full | Weight Change and Its Association with Cardiometabolic Risk Markers in Overweight and Obese Women |
| title_fullStr | Weight Change and Its Association with Cardiometabolic Risk Markers in Overweight and Obese Women |
| title_full_unstemmed | Weight Change and Its Association with Cardiometabolic Risk Markers in Overweight and Obese Women |
| title_short | Weight Change and Its Association with Cardiometabolic Risk Markers in Overweight and Obese Women |
| title_sort | weight change and its association with cardiometabolic risk markers in overweight and obese women |
| url | http://dx.doi.org/10.1155/2020/3198326 |
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