Efficacy and safety of microwave ablation for treatment of follicular thyroid neoplasms: a preliminary study
Objective To assess the feasibility, efficacy, and safety of microwave ablation in treating follicular thyroid neoplasms and suspicious follicular thyroid neoplasms.Methods In this retrospective study, the data of patients treated with microwave ablation for follicular neoplasms from December 2016 t...
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Taylor & Francis Group
2024-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2024.2398558 |
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| author | Xin-Yi Zhou Xin-Yu Yu Ying Wei Zhen-Long Zhao Li-Li Peng Yan Li Jie Wu Shi-Liang Cao Ming-An Yu |
| author_facet | Xin-Yi Zhou Xin-Yu Yu Ying Wei Zhen-Long Zhao Li-Li Peng Yan Li Jie Wu Shi-Liang Cao Ming-An Yu |
| author_sort | Xin-Yi Zhou |
| collection | DOAJ |
| description | Objective To assess the feasibility, efficacy, and safety of microwave ablation in treating follicular thyroid neoplasms and suspicious follicular thyroid neoplasms.Methods In this retrospective study, the data of patients treated with microwave ablation for follicular neoplasms from December 2016 to January 2024 were summarized. The changes in nodule size, volume, technical success rate, disease progression, complete tumor resolution, thyroid function, and complications post-ablation were evaluated.Results Seventy-four patients (15 men, 59 women; mean age 46.3 ± 15.2 years) with follicular neoplasms were included. Over a median follow-up of 13 months, complete ablation was achieved, giving a 100% technical success rate. At the first month post-ablation, the maximum diameter of nodules showed no significant change (p = 0.287). From the third month, both maximum diameter and volume significantly decreased (p < 0.005 for all). Volume reduction rates remained stable at one and three months (p = 0.389 and 0.06, respectively) but increased significantly thereafter (p < 0.005 for all). By 24 months, the median maximum diameter had reduced from 2.3 cm to 0 cm, achieving a median volume reduction rate of 100%. Nodules disappeared completely in 20.3% (15/74). Local recurrence was noted in 2.7% of cases (2/74), with no metastasis or neoplasm-related deaths reported. Thyroid function remained unchanged post-treatment (p > 0.05). The complication and side effect rates were 8.1% and 4.1%, respectively.Conclusions Initial findings suggest microwave ablation is an effective and safe treatment for follicular neoplasms, with low incidences of disease progression and complications, while maintaining thyroid function. |
| format | Article |
| id | doaj-art-5b1595bce5d14cf6b1ae0d5d4decb295 |
| institution | DOAJ |
| issn | 0265-6736 1464-5157 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj-art-5b1595bce5d14cf6b1ae0d5d4decb2952025-08-20T02:44:12ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572024-12-0141110.1080/02656736.2024.2398558Efficacy and safety of microwave ablation for treatment of follicular thyroid neoplasms: a preliminary studyXin-Yi Zhou0Xin-Yu Yu1Ying Wei2Zhen-Long Zhao3Li-Li Peng4Yan Li5Jie Wu6Shi-Liang Cao7Ming-An Yu8Beijing University of Chinese Medicine, Beijing, ChinaZhongshan Medical School, Sun Yat-Sen University, Guangzhou, Guangdong, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaObjective To assess the feasibility, efficacy, and safety of microwave ablation in treating follicular thyroid neoplasms and suspicious follicular thyroid neoplasms.Methods In this retrospective study, the data of patients treated with microwave ablation for follicular neoplasms from December 2016 to January 2024 were summarized. The changes in nodule size, volume, technical success rate, disease progression, complete tumor resolution, thyroid function, and complications post-ablation were evaluated.Results Seventy-four patients (15 men, 59 women; mean age 46.3 ± 15.2 years) with follicular neoplasms were included. Over a median follow-up of 13 months, complete ablation was achieved, giving a 100% technical success rate. At the first month post-ablation, the maximum diameter of nodules showed no significant change (p = 0.287). From the third month, both maximum diameter and volume significantly decreased (p < 0.005 for all). Volume reduction rates remained stable at one and three months (p = 0.389 and 0.06, respectively) but increased significantly thereafter (p < 0.005 for all). By 24 months, the median maximum diameter had reduced from 2.3 cm to 0 cm, achieving a median volume reduction rate of 100%. Nodules disappeared completely in 20.3% (15/74). Local recurrence was noted in 2.7% of cases (2/74), with no metastasis or neoplasm-related deaths reported. Thyroid function remained unchanged post-treatment (p > 0.05). The complication and side effect rates were 8.1% and 4.1%, respectively.Conclusions Initial findings suggest microwave ablation is an effective and safe treatment for follicular neoplasms, with low incidences of disease progression and complications, while maintaining thyroid function.https://www.tandfonline.com/doi/10.1080/02656736.2024.2398558Follicular thyroid neoplasmmicrowave ablationBethesda IVfine-needle aspirationultrasound |
| spellingShingle | Xin-Yi Zhou Xin-Yu Yu Ying Wei Zhen-Long Zhao Li-Li Peng Yan Li Jie Wu Shi-Liang Cao Ming-An Yu Efficacy and safety of microwave ablation for treatment of follicular thyroid neoplasms: a preliminary study International Journal of Hyperthermia Follicular thyroid neoplasm microwave ablation Bethesda IV fine-needle aspiration ultrasound |
| title | Efficacy and safety of microwave ablation for treatment of follicular thyroid neoplasms: a preliminary study |
| title_full | Efficacy and safety of microwave ablation for treatment of follicular thyroid neoplasms: a preliminary study |
| title_fullStr | Efficacy and safety of microwave ablation for treatment of follicular thyroid neoplasms: a preliminary study |
| title_full_unstemmed | Efficacy and safety of microwave ablation for treatment of follicular thyroid neoplasms: a preliminary study |
| title_short | Efficacy and safety of microwave ablation for treatment of follicular thyroid neoplasms: a preliminary study |
| title_sort | efficacy and safety of microwave ablation for treatment of follicular thyroid neoplasms a preliminary study |
| topic | Follicular thyroid neoplasm microwave ablation Bethesda IV fine-needle aspiration ultrasound |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2024.2398558 |
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