Focused Ion Beam in the Study of Biomaterials and Biological Matter
The application of focused ion beam (FIB) techniques in the life sciences has progressed by leaps and bounds over the past decade. A once dedicated ion beam instrument, the focused ion beam today is generally coupled with a plethora of complementary tools such as dual-beam scanning electron microsco...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2012/841961 |
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| _version_ | 1832567725632782336 |
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| author | Kathryn Grandfield Håkan Engqvist |
| author_facet | Kathryn Grandfield Håkan Engqvist |
| author_sort | Kathryn Grandfield |
| collection | DOAJ |
| description | The application of focused ion beam (FIB) techniques in the life sciences has progressed by leaps and bounds over the past decade. A once dedicated ion beam instrument, the focused ion beam today is generally coupled with a plethora of complementary tools such as dual-beam scanning electron microscopy (SEM), environmental SEM, energy dispersive X-ray spectroscopy (EDX), or cryogenic possibilities. All of these additions have contributed to the advancement of focused ion beam use in the study of biomaterials and biological matter. Biomaterials, cells, and their interfaces can be routinely imaged, analyzed, or prepared for techniques such as transmission electron microscopy (TEM) with this comprehensive tool. Herein, we review the uses, advances, and challenges associated with the application of FIB techniques to the life sciences, with particular emphasis on TEM preparation of biomaterials, biological matter, and their interfaces using FIB. |
| format | Article |
| id | doaj-art-5b1047cac38d4960bdaa3d06103140b6 |
| institution | Kabale University |
| issn | 1687-8434 1687-8442 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-5b1047cac38d4960bdaa3d06103140b62025-02-03T01:00:37ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422012-01-01201210.1155/2012/841961841961Focused Ion Beam in the Study of Biomaterials and Biological MatterKathryn Grandfield0Håkan Engqvist1Department of Engineering Sciences, The Å ngström Laboratory, Uppsala University, Uppsala 751 21, SwedenDepartment of Engineering Sciences, The Å ngström Laboratory, Uppsala University, Uppsala 751 21, SwedenThe application of focused ion beam (FIB) techniques in the life sciences has progressed by leaps and bounds over the past decade. A once dedicated ion beam instrument, the focused ion beam today is generally coupled with a plethora of complementary tools such as dual-beam scanning electron microscopy (SEM), environmental SEM, energy dispersive X-ray spectroscopy (EDX), or cryogenic possibilities. All of these additions have contributed to the advancement of focused ion beam use in the study of biomaterials and biological matter. Biomaterials, cells, and their interfaces can be routinely imaged, analyzed, or prepared for techniques such as transmission electron microscopy (TEM) with this comprehensive tool. Herein, we review the uses, advances, and challenges associated with the application of FIB techniques to the life sciences, with particular emphasis on TEM preparation of biomaterials, biological matter, and their interfaces using FIB.http://dx.doi.org/10.1155/2012/841961 |
| spellingShingle | Kathryn Grandfield Håkan Engqvist Focused Ion Beam in the Study of Biomaterials and Biological Matter Advances in Materials Science and Engineering |
| title | Focused Ion Beam in the Study of Biomaterials and Biological Matter |
| title_full | Focused Ion Beam in the Study of Biomaterials and Biological Matter |
| title_fullStr | Focused Ion Beam in the Study of Biomaterials and Biological Matter |
| title_full_unstemmed | Focused Ion Beam in the Study of Biomaterials and Biological Matter |
| title_short | Focused Ion Beam in the Study of Biomaterials and Biological Matter |
| title_sort | focused ion beam in the study of biomaterials and biological matter |
| url | http://dx.doi.org/10.1155/2012/841961 |
| work_keys_str_mv | AT kathryngrandfield focusedionbeaminthestudyofbiomaterialsandbiologicalmatter AT hakanengqvist focusedionbeaminthestudyofbiomaterialsandbiologicalmatter |