Plasmodium berghei liver stage parasites exploit host GABARAP proteins for TFEB activation

Plasmodium berghei liver stage parasites exploit host GABARAP proteins for TFEB activation

Abstract Plasmodium, the causative agent of malaria, infects hepatocytes prior to establishing a symptomatic blood stage infection. During this liver stage development, parasites reside in a parasitophorous vacuole (PV), whose membrane acts as the critical interface between the parasite and the host...

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Bibliographic Details
Main Authors: Jacqueline Schmuckli-Maurer, Annina F. Bindschedler, Rahel Wacker, Oliver M. Würgler, Ruth Rehmann, Timothy Lehmberg, Leon O. Murphy, Thanh N. Nguyen, Michael Lazarou, Jlenia Monfregola, Andrea Ballabio, Volker T. Heussler
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07242-x
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