An ATP-activated spatiotemporally controlled hydrogel prodrug system for treating multidrug-resistant bacteria-infected pressure ulcers

An ATP-activated spatiotemporally controlled hydrogel prodrug system for treating multidrug-resistant bacteria-infected pressure ulcers

Adenosine triphosphate (ATP)-activated prodrug approaches demonstrate potential in antibacterial uses. However, their efficacy frequently faces obstacles due to uncontrolled premature activation and spatiotemporal distribution differences under physiological circumstances. Herein, we present an endo...

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Bibliographic Details
Main Authors: Xiaoliang Qi, Yajing Xiang, Ying Li, Jiajia Wang, Yuxi Chen, Yulong Lan, Jinsong Liu, Jianliang Shen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Bioactive Materials
Subjects:
Prodrug systems
Adenosine triphosphate response
Hydrogels
Multidrug-resistant bacterial infection
Pressure ulcers
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24005206
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