Six-Pack Balancing Act: A Conceptual Model for the Intestinal Lining
The cells chat form the lining of the intestine belong to a class of cells termed 'polarized' or 'asymmetric.' The membranes surrounding these cells show functional differences at the luminal and contraluminal surfaces. The cells line up to form sheets and it is across these shee...
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| Format: | Article |
| Language: | English |
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Wiley
1990-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1990/719831 |
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| _version_ | 1849411678777638912 |
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| author | PK Rangachari |
| author_facet | PK Rangachari |
| author_sort | PK Rangachari |
| collection | DOAJ |
| description | The cells chat form the lining of the intestine belong to a class of
cells termed 'polarized' or 'asymmetric.' The membranes surrounding these cells
show functional differences at the luminal and contraluminal surfaces. The cells
line up to form sheets and it is across these sheers that movement of fluids and
solutes occurs. Such movement occurs in both directions across the lining and
the occurrence of diarrhea or constipation depends to a considerable extent upon
the net result of the absorptive and secretory mechanisms and their modulation
by a host of factors such as neurotransmitters, bacterial products, drugs, etc. This
review provides a simple framework for understanding the dynamics of the gut
lining. Diamond's six-pack model of epithelia is modified to include the dynamic
tension between absorptive and secretory mechanisms. |
| format | Article |
| id | doaj-art-5af18b6ec52d4e348b0aa83c26235b65 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 1990-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-5af18b6ec52d4e348b0aa83c26235b652025-08-20T03:34:42ZengWileyCanadian Journal of Gastroenterology0835-79001990-01-014520120810.1155/1990/719831Six-Pack Balancing Act: A Conceptual Model for the Intestinal LiningPK RangachariThe cells chat form the lining of the intestine belong to a class of cells termed 'polarized' or 'asymmetric.' The membranes surrounding these cells show functional differences at the luminal and contraluminal surfaces. The cells line up to form sheets and it is across these sheers that movement of fluids and solutes occurs. Such movement occurs in both directions across the lining and the occurrence of diarrhea or constipation depends to a considerable extent upon the net result of the absorptive and secretory mechanisms and their modulation by a host of factors such as neurotransmitters, bacterial products, drugs, etc. This review provides a simple framework for understanding the dynamics of the gut lining. Diamond's six-pack model of epithelia is modified to include the dynamic tension between absorptive and secretory mechanisms.http://dx.doi.org/10.1155/1990/719831 |
| spellingShingle | PK Rangachari Six-Pack Balancing Act: A Conceptual Model for the Intestinal Lining Canadian Journal of Gastroenterology |
| title | Six-Pack Balancing Act: A Conceptual Model for the Intestinal Lining |
| title_full | Six-Pack Balancing Act: A Conceptual Model for the Intestinal Lining |
| title_fullStr | Six-Pack Balancing Act: A Conceptual Model for the Intestinal Lining |
| title_full_unstemmed | Six-Pack Balancing Act: A Conceptual Model for the Intestinal Lining |
| title_short | Six-Pack Balancing Act: A Conceptual Model for the Intestinal Lining |
| title_sort | six pack balancing act a conceptual model for the intestinal lining |
| url | http://dx.doi.org/10.1155/1990/719831 |
| work_keys_str_mv | AT pkrangachari sixpackbalancingactaconceptualmodelfortheintestinallining |