New acute onset of ocular myasthenia gravis after COVID-19 vaccine: A case report

Reports have shown the association of coronavirus disease 2019 (COVID-19) with several neuromuscular disorders. Myasthenia gravis (MG) is an autoimmune disease in which antibodies bind to acetyl choline receptors in the postsynaptic membrane at the neuromuscular junction. The characteristic clinical...

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Main Authors: Himani T. Chaturvedi, Varsha Patel, Rahul Vasava, Chandrashekher Chaturvedi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-02-01
Series:Journal of Family Medicine and Primary Care
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Online Access:https://journals.lww.com/10.4103/jfmpc.jfmpc_1359_22
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author Himani T. Chaturvedi
Varsha Patel
Rahul Vasava
Chandrashekher Chaturvedi
author_facet Himani T. Chaturvedi
Varsha Patel
Rahul Vasava
Chandrashekher Chaturvedi
author_sort Himani T. Chaturvedi
collection DOAJ
description Reports have shown the association of coronavirus disease 2019 (COVID-19) with several neuromuscular disorders. Myasthenia gravis (MG) is an autoimmune disease in which antibodies bind to acetyl choline receptors in the postsynaptic membrane at the neuromuscular junction. The characteristic clinical feature of the disease is weakness of the ocular muscle, bulbar muscle, and extremity muscles; when the weakness is limited to the ocular muscle only, the condition is known as ocular myasthenia gravis. Diagnosis is usually confirmed by the acetylcholine receptor antibodies. Symptoms of MG may be aggravated by various types of infections and medications. Here, we are presenting a rare case of a new and acute onset of ocular MG presented after administration of Covishield vaccine.
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issn 2249-4863
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publishDate 2023-02-01
publisher Wolters Kluwer Medknow Publications
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spelling doaj-art-5ae7cfc845464319b0d70f3d2bf9af1d2025-08-20T02:13:44ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352023-02-0112239439610.4103/jfmpc.jfmpc_1359_22New acute onset of ocular myasthenia gravis after COVID-19 vaccine: A case reportHimani T. ChaturvediVarsha PatelRahul VasavaChandrashekher ChaturvediReports have shown the association of coronavirus disease 2019 (COVID-19) with several neuromuscular disorders. Myasthenia gravis (MG) is an autoimmune disease in which antibodies bind to acetyl choline receptors in the postsynaptic membrane at the neuromuscular junction. The characteristic clinical feature of the disease is weakness of the ocular muscle, bulbar muscle, and extremity muscles; when the weakness is limited to the ocular muscle only, the condition is known as ocular myasthenia gravis. Diagnosis is usually confirmed by the acetylcholine receptor antibodies. Symptoms of MG may be aggravated by various types of infections and medications. Here, we are presenting a rare case of a new and acute onset of ocular MG presented after administration of Covishield vaccine.https://journals.lww.com/10.4103/jfmpc.jfmpc_1359_22covid-19neuromuscular junctionocular myasthenia gravis
spellingShingle Himani T. Chaturvedi
Varsha Patel
Rahul Vasava
Chandrashekher Chaturvedi
New acute onset of ocular myasthenia gravis after COVID-19 vaccine: A case report
Journal of Family Medicine and Primary Care
covid-19
neuromuscular junction
ocular myasthenia gravis
title New acute onset of ocular myasthenia gravis after COVID-19 vaccine: A case report
title_full New acute onset of ocular myasthenia gravis after COVID-19 vaccine: A case report
title_fullStr New acute onset of ocular myasthenia gravis after COVID-19 vaccine: A case report
title_full_unstemmed New acute onset of ocular myasthenia gravis after COVID-19 vaccine: A case report
title_short New acute onset of ocular myasthenia gravis after COVID-19 vaccine: A case report
title_sort new acute onset of ocular myasthenia gravis after covid 19 vaccine a case report
topic covid-19
neuromuscular junction
ocular myasthenia gravis
url https://journals.lww.com/10.4103/jfmpc.jfmpc_1359_22
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AT varshapatel newacuteonsetofocularmyastheniagravisaftercovid19vaccineacasereport
AT rahulvasava newacuteonsetofocularmyastheniagravisaftercovid19vaccineacasereport
AT chandrashekherchaturvedi newacuteonsetofocularmyastheniagravisaftercovid19vaccineacasereport