Sufficiently activated mature natural killer cells derived from peripheral blood mononuclear cells substantially enhance antitumor activity

Abstract Background Peripheral blood‐derived natural killer (NK) cells spontaneously lyse tumor cells without prior sensitization. However, NK cells in peripheral blood (PBNK cells) are in a resting state and exhibit inhibitory phenotypes and impaired cytotoxicity. Thus, strengthening the cytotoxic...

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Bibliographic Details
Main Authors: Chuanling Liu, Yingying Li, Yanrong Li, Meng Hu, Haiyan Wang, Shasha Lu, Zhao Li, Dilinuer Dilimulati, Shunchang Jiao, Shelian Lu, Weihong Zhao
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Immunity, Inflammation and Disease
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Online Access:https://doi.org/10.1002/iid3.1143
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