Progression of vertebral fractures in metastatic melanoma and non-small cell lung cancer patients given immune checkpoint inhibitors

Progression of vertebral fractures in metastatic melanoma and non-small cell lung cancer patients given immune checkpoint inhibitors

Introduction: The immune system mediates important effects on bone metabolism, but little has been done to understand immunotherapy’s role in this interaction. This study aims to describe and identify risk factors for the occurrence and/or exacerbation of vertebral fractures (vertebral fracture prog...

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Main Authors: Marco Meazza Prina, Andrea Alberti, Valeria Tovazzi, Marco Ravanelli, Greta Schivardi, Alice Baggi, Luca Ammoni, Lucilla Guarneri, Francesca Salvotti, Manuel Zamparini, Davide Farina, Margherita Parolise, Salvatore Grisanti, Alfredo Berruti
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Bone Oncology
Subjects:
Immune checkpoint inhibitors
Melanoma
Non-small cell lung cancer
Immune-related adverse events
Bone fractures
Steroid therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137424001222
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