Thrombomodulin resistance as a novel prothrombotic pathway in COVID-19

Abstract Hypercoagulability and endothelial dysfunction are strongly involved in the worsening of the clinical condition in COVID-19 patients. In severe cases, the inflammatory process triggers the release of angiopoietin 2, which could decrease circulating thrombomodulin (TM), a major regulatory me...

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Bibliographic Details
Main Authors: Ana Marco-Rico, Adrián Montaño, Francisco López-Jaime, Ihosvany Fernández-Bello, Pascual Marco-Vera
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-15679-1
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