Pan-cancer drivers of metastasis

Pan-cancer drivers of metastasis

Abstract Metastasis remains a leading cause of cancer-related mortality, irrespective of the primary tumour origin. However, the core gene regulatory program governing distinct stages of metastasis across cancers remains poorly understood. We investigate this through single-cell transcriptome analys...

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Bibliographic Details
Main Authors: Ryan Lusby, Engin Demirdizen, Mohammed Inayatullah, Paramita Kundu, Oscar Maiques, Ziyi Zhang, Mikkel Green Terp, Victoria Sanz-Moreno, Vijay K. Tiwari
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Cancer
Subjects:
Transcription Factors
Gene regulation
Single-cell heterogeneity
Metastasis
Cancer
Online Access:https://doi.org/10.1186/s12943-024-02182-w
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