Pituitary Apoplexy Presenting With Oculomotor Nerve Palsy and Headache as the Initial Symptoms: A Case Report
ABSTRACT Pituitary apoplexy is a rare clinical syndrome. This report presents a case with initial symptoms of oculomotor nerve palsy and headache. A 48‐year‐old patient reported blurred vision in the right eye for 1 month, followed by a sudden onset of left eyelid ptosis and a 1‐day headache. Labora...
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Wiley
2025-02-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.70178 |
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| author | Qifan Hou Lixin Xu Jing Yi |
| author_facet | Qifan Hou Lixin Xu Jing Yi |
| author_sort | Qifan Hou |
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| description | ABSTRACT Pituitary apoplexy is a rare clinical syndrome. This report presents a case with initial symptoms of oculomotor nerve palsy and headache. A 48‐year‐old patient reported blurred vision in the right eye for 1 month, followed by a sudden onset of left eyelid ptosis and a 1‐day headache. Laboratory tests revealed normal pituitary function, except for an elevated growth hormone level (> 36.600 μg/L). Preoperative computed tomography (CT) and magnetic resonance imaging (MRI) scans indicated space‐occupying lesion in the sellar region. The lesion was subsequently resected via transnasal subtotal surgery. Histopathological and immunohistochemical analyses confirmed a pituitary adenoma with infarction. The patient received hydrocortisone preoperatively and prednisone and levothyroxine postoperatively. On the second postoperative day, the headache resolved, and the left eyelid regained normal function within 2 weeks. Pituitary apoplexy is extremely rare, with initial presentations of oculomotor nerve palsy being exceptionally uncommon. Early diagnosis and prompt surgical intervention are essential to preserve pituitary function and rapidly alleviate cranial nerve dysfunction. |
| format | Article |
| id | doaj-art-5ac2e59e376342aeb6cda645a4fb9637 |
| institution | OA Journals |
| issn | 2050-0904 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-5ac2e59e376342aeb6cda645a4fb96372025-08-20T02:15:51ZengWileyClinical Case Reports2050-09042025-02-01132n/an/a10.1002/ccr3.70178Pituitary Apoplexy Presenting With Oculomotor Nerve Palsy and Headache as the Initial Symptoms: A Case ReportQifan Hou0Lixin Xu1Jing Yi2Department of Neurosurgery, Changde Hospital, Xiangya School of Medicine Central South University (The First People's Hospital of Changde City) Changde Hunan ChinaDepartment of Neurosurgery, Changde Hospital, Xiangya School of Medicine Central South University (The First People's Hospital of Changde City) Changde Hunan ChinaDepartment of Neurosurgery, Changde Hospital, Xiangya School of Medicine Central South University (The First People's Hospital of Changde City) Changde Hunan ChinaABSTRACT Pituitary apoplexy is a rare clinical syndrome. This report presents a case with initial symptoms of oculomotor nerve palsy and headache. A 48‐year‐old patient reported blurred vision in the right eye for 1 month, followed by a sudden onset of left eyelid ptosis and a 1‐day headache. Laboratory tests revealed normal pituitary function, except for an elevated growth hormone level (> 36.600 μg/L). Preoperative computed tomography (CT) and magnetic resonance imaging (MRI) scans indicated space‐occupying lesion in the sellar region. The lesion was subsequently resected via transnasal subtotal surgery. Histopathological and immunohistochemical analyses confirmed a pituitary adenoma with infarction. The patient received hydrocortisone preoperatively and prednisone and levothyroxine postoperatively. On the second postoperative day, the headache resolved, and the left eyelid regained normal function within 2 weeks. Pituitary apoplexy is extremely rare, with initial presentations of oculomotor nerve palsy being exceptionally uncommon. Early diagnosis and prompt surgical intervention are essential to preserve pituitary function and rapidly alleviate cranial nerve dysfunction.https://doi.org/10.1002/ccr3.70178case reportheadacheoculomotor nerve palsypituitary apoplexy |
| spellingShingle | Qifan Hou Lixin Xu Jing Yi Pituitary Apoplexy Presenting With Oculomotor Nerve Palsy and Headache as the Initial Symptoms: A Case Report Clinical Case Reports case report headache oculomotor nerve palsy pituitary apoplexy |
| title | Pituitary Apoplexy Presenting With Oculomotor Nerve Palsy and Headache as the Initial Symptoms: A Case Report |
| title_full | Pituitary Apoplexy Presenting With Oculomotor Nerve Palsy and Headache as the Initial Symptoms: A Case Report |
| title_fullStr | Pituitary Apoplexy Presenting With Oculomotor Nerve Palsy and Headache as the Initial Symptoms: A Case Report |
| title_full_unstemmed | Pituitary Apoplexy Presenting With Oculomotor Nerve Palsy and Headache as the Initial Symptoms: A Case Report |
| title_short | Pituitary Apoplexy Presenting With Oculomotor Nerve Palsy and Headache as the Initial Symptoms: A Case Report |
| title_sort | pituitary apoplexy presenting with oculomotor nerve palsy and headache as the initial symptoms a case report |
| topic | case report headache oculomotor nerve palsy pituitary apoplexy |
| url | https://doi.org/10.1002/ccr3.70178 |
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