Methicillin-resistant Staphylococcus aureus in Saudi Arabia: genomic evidence of recent clonal expansion and plasmid-driven resistance dissemination

Methicillin-resistant Staphylococcus aureus in Saudi Arabia: genomic evidence of recent clonal expansion and plasmid-driven resistance dissemination

ObjectivesStaphylococcus aureus is a leading cause of hospital-acquired infections worldwide. Over recent decades, methicillin-resistant Staphylococcus aureus (MRSA), which is resistant to multiple antimicrobials, has emerged as a significant pathogenic strain in both hospital and community settings...

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Main Authors: Ahmed Yousef Alhejaili, Ge Zhou, Heba Halawa, Jiayi Huang, Omniya Fallatah, Raneem Hirayban, Sara Iftikhar, Abrar AlAsmari, Mathew Milner, Manuel Banzhaf, Albandari A. Alzaidi, Ahmad A. Rajeh, Maram Abdulmohsen Al-Otaiby, Sarah S. Alabbad, Doua Bukhari, Abdullah N. Aljurayyan, Alanoud T. Aljasham, Zeyad A. Alzeyadi, Sulaiman M. Alajel, Rawan Hamdan Alanazi, Majed Alghoribi, Mashal M. Almutairi, Arnab Pain, Abiola Senok, Danesh Moradigaravand, Waleed Al Salem
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Microbiology
Subjects:
MRSA
MSSA
bloodstream infection
ST
precision epidemiology
Kingdom of Saudi Arabia
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1602985/full
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